HitPredict

Interactor 1: MET (P08581)
Hepatocyte growth factor receptor (HGF receptor) (EC 2.7.10.1) (HGF/SF receptor) (Proto-oncogene c-Met) (Scatter factor receptor) (SF receptor) (Tyrosine-protein kinase Met)
Gene: MET

Interactor 2: PTPRO (Q16827)
Receptor-type tyrosine-protein phosphatase O (R-PTP-O) (EC 3.1.3.48) (Glomerular epithelial protein 1) (Protein tyrosine phosphatase U2) (PTP-U2) (PTPase U2)
Gene: PTPRO

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.63 1.00 0.799

The method score is based on:

Property Details
Experiments 28330616, 19167335
Identification Methods affinity chromatography technology, pull down, phosphatase assay
Interaction Type physical association, association, dephosphorylation reaction

The annotation score is based on:

Property Details
Interacting Pfam domains PK_Tyr_Ser-Thr~fn3, PK_Tyr_Ser-Thr~Y_phosphatase
Common GO terms GO:0005886 - plasma membrane
GO:0016020 - membrane
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 1390
Hs

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Last updated: 15 Jul 2024