HitPredict

Interactor 1: MET (P08581)
Hepatocyte growth factor receptor (HGF receptor) (EC 2.7.10.1) (HGF/SF receptor) (Proto-oncogene c-Met) (Scatter factor receptor) (SF receptor) (Tyrosine-protein kinase Met)
Gene: MET

Interactor 2: SPSB1 (Q96BD6)
SPRY domain-containing SOCS box protein 1 (SSB-1)
Gene: SPSB1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	15713673
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1390 Hs			1 273
+	Hs
		441549 MET_HUMAN (1-1390): 0: 1283: 100.00		SPSB4_HUMAN (1-273): 1.02e-119: 345: 74.73
+	Hs
		441559 MET_HUMAN (1-1390): 0: 1283: 100.00		SPSB2_HUMAN (1-273): 3.23e-94: 280: 50.18
+	Hs
		441522 MET_HUMAN (1-1390): 0: 1283: 100.00		SPSB3_HUMAN (54-270): 5.39e-59: 193: 25.11
+	Hs
		441558 MET_HUMAN (1-1390): 0: 1283: 100.00		RANB9_HUMAN (55-273): 2.31e-43: 158: 14.41
+	Hs
		441525 MET_HUMAN (1-1390): 0: 1283: 100.00		RBP10_HUMAN (55-273): 2.24e-41: 151: 16.67
+	Hs
		441527 MET_HUMAN (1-1390): 0: 1283: 100.00		TRI67_HUMAN (52-232): 7.58e-36: 137: 17.11
+	Hs
		981903 RON_HUMAN (23-1390): 0: 934: 32.70		DDX1_HUMAN (6-237): 5.11e-58: 198: 18.30
+	Hs
		665644 EPHB2_HUMAN (597-1389): 7.92e-156: 500: 18.91		SPSB1_HUMAN (1-273): 1.09e-124: 357: 100.00
+	Hs
		872615 EPHB1_HUMAN (597-1389): 2.34e-158: 505: 18.76		SPSB4_HUMAN (1-273): 1.02e-119: 345: 74.73
+	Hs
		665641 EPHB2_HUMAN (597-1389): 7.92e-156: 500: 18.91		SPSB4_HUMAN (1-273): 1.02e-119: 345: 74.73
+	Hs
		665651 EPHB2_HUMAN (597-1389): 7.92e-156: 500: 18.91		SPSB2_HUMAN (1-273): 3.23e-94: 280: 50.18
+	Hs
		472678 EPHB2_HUMAN (597-1389): 7.92e-156: 500: 18.91		FBSP1_HUMAN (22-230): 1.1e-69: 218: 36.02
+	Hs
		665406 EPHA3_HUMAN (584-1379): 1.09e-179: 561: 18.13		TRI67_HUMAN (52-232): 7.58e-36: 137: 17.11
+	Hs
		665616 EPHB2_HUMAN (597-1389): 7.92e-156: 500: 18.91		TRI67_HUMAN (52-232): 7.58e-36: 137: 17.11
+	Hs
		872543 EPHB4_HUMAN (736-1342): 2.91e-128: 424: 21.72		TRI67_HUMAN (52-232): 7.58e-36: 137: 17.11
+	Hs
		850481 PLXA3_HUMAN (381-1019): 8.58e-111: 388: 17.82		TRI67_HUMAN (52-232): 7.58e-36: 137: 17.11
+	Hs
		1140850 PLXB3_HUMAN (513-1016): 4.76e-116: 404: 21.78		RN123_HUMAN (87-214): 2.81e-12: 68.7: 22.14
+	Hs
		1171805 PLXA4_HUMAN (458-1070): 1.66e-78: 288: 19.39		TRI67_HUMAN (52-232): 7.58e-36: 137: 17.11
+	Hs
		195981 PLXB1_HUMAN (464-1030): 8.24e-66: 248: 20.88		TRI67_HUMAN (52-232): 7.58e-36: 137: 17.11
+	Hs
		1140789 PLXA4_HUMAN (458-1070): 1.66e-78: 288: 19.39		RN123_HUMAN (87-214): 2.81e-12: 68.7: 22.14