HitPredict

Interactor 1: MET (P08581)
Hepatocyte growth factor receptor (HGF receptor) (EC 2.7.10.1) (HGF/SF receptor) (Proto-oncogene c-Met) (Scatter factor receptor) (SF receptor) (Tyrosine-protein kinase Met)
Gene: MET

Interactor 2: DNJA3 (Q96EY1)
DnaJ homolog subfamily A member 3, mitochondrial (DnaJ protein Tid-1) (hTid-1) (Hepatocellular carcinoma-associated antigen 57) (Tumorous imaginal discs protein Tid56 homolog)
Gene: DNAJA3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.621

Property	Details
Experiments	35384245, 21242965
Identification Methods	affinity chromatography technology, proximity labelling technology, pull down, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 1390 Hs			1 480
+	Hs
		609471 FGFR3_HUMAN (982-1360): 5.32e-108: 363: 31.83		DNJA3_HUMAN (1-480): 0: 553: 100.00
+	Hs
		435729 IGF1R_HUMAN (1084-1337): 2.07e-56: 217: 42.16		DNJA3_HUMAN (1-480): 0: 553: 100.00
+	Hs
		411469 INSR_HUMAN (1084-1335): 3.87e-55: 213: 42.11		DNJA3_HUMAN (1-480): 0: 553: 100.00
+	Hs
		674347 UFO_HUMAN (1078-1333): 5.27e-66: 243: 45.90		DNJA1_HUMAN (89-468): 2.73e-123: 367: 26.43
+	Hs
		243305 UFO_HUMAN (1078-1333): 5.27e-66: 243: 45.90		DNJA2_HUMAN (89-465): 4.81e-122: 364: 26.38
+	Hs
		681414 TYRO3_HUMAN (1053-1341): 6.19e-65: 240: 41.67		DNJA1_HUMAN (89-468): 2.73e-123: 367: 26.43
+	Hs
		435551 IGF1R_HUMAN (1084-1337): 2.07e-56: 217: 42.16		DNJA1_HUMAN (89-468): 2.73e-123: 367: 26.43
+	Hs
		243262 IGF1R_HUMAN (1084-1337): 2.07e-56: 217: 42.16		DNJA2_HUMAN (89-465): 4.81e-122: 364: 26.38
+	Hs
		411313 INSR_HUMAN (1084-1335): 3.87e-55: 213: 42.11		DNJA1_HUMAN (89-468): 2.73e-123: 367: 26.43
+	Hs
		243254 INSR_HUMAN (1084-1335): 3.87e-55: 213: 42.11		DNJA2_HUMAN (89-465): 4.81e-122: 364: 26.38
+	Hs
		681357 CSK_HUMAN (1082-1340): 5.46e-52: 192: 40.77		DNJA1_HUMAN (89-468): 2.73e-123: 367: 26.43
+	Dm
		448256 INSR_DROME (1084-1335): 8e-54: 209: 39.49		Q9VFV9_DROME (89-469): 4.7e-111: 335: 23.19