HitPredict

Interactor 1: MYL3 (P08590)
Myosin light chain 3 (Cardiac myosin light chain 1) (CMLC1) (Myosin light chain 1, slow-twitch muscle B/ventricular isoform) (MLC1SB) (Ventricular myosin alkali light chain) (Ventricular myosin light chain 1) (VLCl) (Ventricular/slow twitch myosin alkali light chain) (MLC-lV/sb)
Gene: MYL3

Interactor 2: IQGA1 (P46940)
Ras GTPase-activating-like protein IQGAP1 (p195)
Gene: IQGAP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005509 - calcium ion binding GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 195 Hs			1 1657
+	Hs
		409454 MYL1_HUMAN (34-194): 7.23e-69: 209: 75.16		IQGA1_HUMAN (1-1657): 0: 1732: 100.00
+	Hs
		521679 MYL4_HUMAN (37-194): 3.32e-57: 180: 82.91		IQGA1_HUMAN (1-1657): 0: 1732: 100.00
+	Hs
		809231 MYL6_HUMAN (45-194): 1.36e-54: 172: 73.33		IQGA1_HUMAN (1-1657): 0: 1732: 100.00
+	Hs
		538647 MYL6B_HUMAN (1-194): 1.22e-50: 163: 57.90		IQGA1_HUMAN (1-1657): 0: 1732: 100.00
+	Hs
		483913 CALM1_HUMAN (35-119): 1.11e-11: 61.9: 22.35		IQGA1_HUMAN (1-1657): 0: 1732: 100.00
+	Hs
		483984 CALM2_HUMAN (35-119): 1.11e-11: 61.9: 22.35		IQGA1_HUMAN (1-1657): 0: 1732: 100.00
+	Hs
		484079 CALM3_HUMAN (35-119): 1.11e-11: 61.9: 22.35		IQGA1_HUMAN (1-1657): 0: 1732: 100.00
+	Hs
		648473 CALL3_HUMAN (35-121): 1.59e-11: 61.1: 19.54		IQGA1_HUMAN (1-1657): 0: 1732: 100.00
+	Hs
		521684 MYL4_HUMAN (37-194): 3.32e-57: 180: 82.91		IQGA3_HUMAN (13-1657): 0: 1561: 58.87
+	Hs
		891555 MYL6_HUMAN (45-194): 1.36e-54: 172: 73.33		IQGA3_HUMAN (13-1657): 0: 1561: 58.87
+	Hs
		538684 MYL6B_HUMAN (1-194): 1.22e-50: 163: 57.90		IQGA3_HUMAN (13-1657): 0: 1561: 58.87
+	Hs
		57913 B4DJ51_HUMAN (35-119): 1.11e-11: 61.9: 22.35		A2RRC9_HUMAN (13-1657): 0: 1566: 58.93
+	Hs
		483946 CALM1_HUMAN (35-119): 1.11e-11: 61.9: 22.35		IQGA3_HUMAN (13-1657): 0: 1561: 58.87
+	Hs
		484020 CALM2_HUMAN (35-119): 1.11e-11: 61.9: 22.35		IQGA3_HUMAN (13-1657): 0: 1561: 58.87
+	Hs
		484161 CALM3_HUMAN (35-119): 1.11e-11: 61.9: 22.35		IQGA3_HUMAN (13-1657): 0: 1561: 58.87
+	Hs
		891518 MYL6_HUMAN (45-194): 1.36e-54: 172: 73.33		IQGA2_HUMAN (254-1657): 0: 1321: 54.09
+	Hs
		648499 CALL3_HUMAN (35-121): 1.59e-11: 61.1: 19.54		IQGA2_HUMAN (254-1657): 0: 1321: 54.09
+	Hs
		891587 MYL6_HUMAN (45-194): 1.36e-54: 172: 73.33		SYGP1_HUMAN (635-1477): 1.49e-108: 380: 12.26
+	Hs
		483957 CALM1_HUMAN (35-119): 1.11e-11: 61.9: 22.35		SYGP1_HUMAN (635-1477): 1.49e-108: 380: 12.26
+	Sp
		144978 CALM_SCHPO (35-121): 6.44e-13: 64.9: 22.99		IQG1_SCHPO (11-204): 6.98e-41: 167: 38.14