HitPredict

Interactor 1: CFAH (P08603)
Complement factor H (H factor 1)
Gene: CFH

Interactor 2: PTX3 (P26022)
Pentraxin-related protein PTX3 (Pentaxin-related protein PTX3) (Tumor necrosis factor alpha-induced protein 5) (TNF alpha-induced protein 5) (Tumor necrosis factor-inducible gene 14 protein) (TSG-14)
Gene: PTX3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	19050261, 29374201
Identification Methods	surface plasmon resonance, solid phase assay, enzyme linked immunosorbent assay
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region GO:0005615 - extracellular space
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 1231 Hs			1 381
+	Hs
		362354 CFAH_HUMAN (1-1231): 0: 769: 100.00		CRP_HUMAN (166-375): 8e-81: 248: 23.59
+	Hs
		555713 LYAM3_HUMAN (1-145): 2.93e-10: 66.9: 14.29		PTX3_HUMAN (1-381): 0: 543: 100.00
+	Hs
		362382 FHR3_HUMAN (206-497): 3.11e-30: 125: 23.95		CRP_HUMAN (166-375): 8e-81: 248: 23.59
+	Hs
		362420 C4BPA_HUMAN (987-1230): 7.14e-23: 106: 21.01		SAMP_HUMAN (163-375): 1.22e-77: 240: 21.60
+	Hs
		362400 FHR4_HUMAN (11-385): 2.11e-19: 95.8: 20.05		CRP_HUMAN (166-375): 8e-81: 248: 23.59