HitPredict

Interactor 1: CFAH (P08603)
Complement factor H (H factor 1)
Gene: CFH

Interactor 2: SMAD3 (P84022)
Mothers against decapentaplegic homolog 3 (MAD homolog 3) (Mad3) (Mothers against DPP homolog 3) (hMAD-3) (JV15-2) (SMAD family member 3) (SMAD 3) (Smad3) (hSMAD3)
Gene: SMAD3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.439

Property	Details
Experiments	21988832
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 1231 Hs			1 425
+	Hs
		950250 CSMD1_HUMAN (21-1137): 4.51e-18: 93.1: 12.93		SMAD3_HUMAN (1-425): 0: 636: 100.00
+	Hs
		950260 NOTC4_HUMAN (437-1126): 2.48e-17: 90.4: 13.32		SMAD3_HUMAN (1-425): 0: 636: 100.00
+	Hs
		950163 PAPP1_HUMAN (1-179): 3.13e-15: 83.4: 17.46		SMAD3_HUMAN (1-425): 0: 636: 100.00
+	Hs
		950199 SVEP1_HUMAN (1001-1231): 1.47e-09: 65: 14.10		SMAD3_HUMAN (1-425): 0: 636: 100.00
+	Hs
		1078639 NOTC4_HUMAN (437-1126): 2.48e-17: 90.4: 13.32		SMAD2_HUMAN (1-425): 0: 589: 83.73
+	Hs
		1028132 PAPP1_HUMAN (1-179): 3.13e-15: 83.4: 17.46		SMAD2_HUMAN (1-425): 0: 589: 83.73
+	Hs
		171392 PAPP1_HUMAN (1-179): 3.13e-15: 83.4: 17.46		SMAD9_HUMAN (1-425): 0: 559: 58.62
+	Hs
		171403 SVEP1_HUMAN (1001-1231): 1.47e-09: 65: 14.10		SMAD9_HUMAN (1-425): 0: 559: 58.62
+	Hs
		1035564 NOTC4_HUMAN (437-1126): 2.48e-17: 90.4: 13.32		SMAD4_HUMAN (23-414): 1.55e-117: 355: 33.21
+	Hs
		1035611 TEN3_HUMAN (942-1229): 1.46e-09: 65: 13.13		SMAD4_HUMAN (23-414): 1.55e-117: 355: 33.21