HitPredict

Interactor 1: RU17 (P08621)
U1 small nuclear ribonucleoprotein 70 kDa (U1 snRNP 70 kDa) (U1-70K) (snRNP70)
Gene: SNRNP70

Interactor 2: RBM11 (P57052)
Splicing regulator RBM11 (RNA-binding motif protein 11)
Gene: RBM11

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	1.00	0.698

Property	Details
Experiments	35914814
Identification Methods	two hybrid, two hybrid fragment pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1, RRM_1~U1snRNP70_N
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0016607 - nuclear speck
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 437 Hs			1 281
+	Hs
		516371 PABP1_HUMAN (4-361): 2.68e-53: 190: 11.08		RBMS1_HUMAN (1-267): 1.48e-36: 136: 14.44
+	Hs
		516623 PABP1_HUMAN (4-361): 2.68e-53: 190: 11.08		DAZL_HUMAN (3-264): 6.63e-33: 123: 19.32
+	Hs
		441893 RU17_HUMAN (1-437): 8.99e-46: 165: 100.00		RBMS1_HUMAN (1-267): 1.48e-36: 136: 14.44
+	Hs
		516484 PABP1_HUMAN (4-361): 2.68e-53: 190: 11.08		ELAV2_HUMAN (2-160): 8.91e-23: 98: 16.36
+	Hs
		516495 PABP1_HUMAN (4-361): 2.68e-53: 190: 11.08		PABP4_HUMAN (3-99): 7.21e-21: 94.1: 23.47
+	Hs
		516339 PABP1_HUMAN (4-361): 2.68e-53: 190: 11.08		PABP1_HUMAN (2-99): 9.14e-20: 90.7: 22.22
+	Hs
		516689 PABP1_HUMAN (4-361): 2.68e-53: 190: 11.08		PABP3_HUMAN (11-95): 9.44e-18: 84.8: 27.06
+	Mm
		665745 PABP1_MOUSE (4-361): 4.42e-53: 189: 11.08		TIA1_MOUSE (5-98): 4.45e-16: 79.1: 27.66
+	Hs
		442112 RU17_HUMAN (1-437): 8.99e-46: 165: 100.00		ELAV2_HUMAN (2-160): 8.91e-23: 98: 16.36
+	Hs
		442125 RU17_HUMAN (1-437): 8.99e-46: 165: 100.00		PABP4_HUMAN (3-99): 7.21e-21: 94.1: 23.47
+	Hs
		442178 RU17_HUMAN (1-437): 8.99e-46: 165: 100.00		SF3B4_HUMAN (9-111): 3.63e-21: 94: 26.67
+	Hs
		516744 PABP1_HUMAN (4-361): 2.68e-53: 190: 11.08		PPIE_HUMAN (10-90): 1.92e-12: 67.8: 32.96
+	Hs
		441852 RU17_HUMAN (1-437): 8.99e-46: 165: 100.00		PABP1_HUMAN (2-99): 9.14e-20: 90.7: 22.22
+	Hs
		442183 RU17_HUMAN (1-437): 8.99e-46: 165: 100.00		ELAV1_HUMAN (2-133): 2.8e-20: 90.6: 17.24
+	Mm
		857334 RU17_MOUSE (1-437): 1.33e-49: 176: 89.78		TIA1_MOUSE (5-98): 4.45e-16: 79.1: 27.66
+	Sc
		376897 RU17_YEAST (3-297): 9.1e-46: 162: 26.58		PABP_YEAST (6-99): 1.95e-18: 86.8: 23.16
+	Hs
		441896 RU17_HUMAN (1-437): 8.99e-46: 165: 100.00		TIA1_HUMAN (5-98): 3.85e-16: 79.5: 27.66
+	Hs
		474034 PABP5_HUMAN (4-350): 4.45e-37: 141: 11.14		PAB4L_HUMAN (8-87): 4.68e-23: 98.7: 25.00
+	Sc
		694189 RU17_YEAST (3-297): 9.1e-46: 162: 26.58		PUB1_YEAST (6-94): 3.99e-14: 73.6: 29.21