HitPredict

Interactor 1: RU17 (P08621)
U1 small nuclear ribonucleoprotein 70 kDa (U1 snRNP 70 kDa) (U1-70K) (snRNP70)
Gene: SNRNP70

Interactor 2: CSK21 (P68400)
Casein kinase II subunit alpha (CK II alpha) (EC 2.7.11.1)
Gene: CSNK2A1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.66	1.00	0.812

Property	Details
Experiments	29802200, 22113938
Identification Methods	affinity chromatography technology, enzymatic study, protein kinase assay
Interaction Type	physical association, direct interaction, phosphorylation reaction

Property	Details
Interacting Pfam domains	Pkinase~RRM_1
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 437 Hs			1 391
+	Hs
		516457 PABP1_HUMAN (4-361): 2.68e-53: 190: 11.08		CSK21_HUMAN (1-391): 2.89e-136: 396: 100.00
+	Hs
		516362 PABP1_HUMAN (4-361): 2.68e-53: 190: 11.08		CDK2_HUMAN (36-330): 5.34e-122: 356: 29.74
+	Hs
		516419 PABP1_HUMAN (4-361): 2.68e-53: 190: 11.08		GSK3B_HUMAN (39-389): 1.2e-112: 337: 29.12
+	Hs
		934135 PABP4_HUMAN (2-265): 2.72e-31: 128: 11.81		CSK21_HUMAN (1-391): 2.89e-136: 396: 100.00
+	Hs
		441877 RU17_HUMAN (1-437): 8.99e-46: 165: 100.00		CSK22_HUMAN (1-334): 4.14e-119: 351: 85.08
+	Hs
		441958 RU17_HUMAN (1-437): 8.99e-46: 165: 100.00		GSK3B_HUMAN (39-389): 1.2e-112: 337: 29.12
+	Hs
		625657 RBM7_HUMAN (96-357): 1.08e-35: 134: 18.73		CDK2_HUMAN (36-330): 5.34e-122: 356: 29.74
+	Hs
		586881 PPIL4_HUMAN (63-356): 2.16e-35: 138: 17.17		CSK22_HUMAN (1-334): 4.14e-119: 351: 85.08
+	Hs
		111287 J3KPD3_HUMAN (96-357): 1.34e-34: 131: 17.91		CDK2_HUMAN (36-330): 5.34e-122: 356: 29.74
+	Sc
		376615 PABP_YEAST (2-281): 3.47e-29: 121: 12.15		CSK21_YEAST (1-329): 6.88e-113: 336: 54.32
+	Hs
		235715 HNRPQ_HUMAN (4-313): 1.11e-16: 84.2: 13.55		CDK2_HUMAN (36-330): 5.34e-122: 356: 29.74