HitPredict

Interactor 1: RU17 (P08621)
U1 small nuclear ribonucleoprotein 70 kDa (U1 snRNP 70 kDa) (U1-70K) (snRNP70)
Gene: SNRNP70

Interactor 2: RUNX1 (Q01196)
Runt-related transcription factor 1 (Acute myeloid leukemia 1 protein) (Core-binding factor subunit alpha-2) (CBF-alpha-2) (Oncogene AML-1) (Polyomavirus enhancer-binding protein 2 alpha B subunit) (PEA2-alpha B) (PEBP2-alpha B) (SL3-3 enhancer factor 1 alpha B subunit) (SL3/AKV core-binding factor alpha B subunit)
Gene: RUNX1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.614

Property	Details
Experiments	28533407, 35914814
Identification Methods	affinity chromatography technology, two hybrid, two hybrid fragment pooling approach
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 437 Hs			1 453
+	Hs
		516472 PABP1_HUMAN (4-361): 2.68e-53: 190: 11.08		RUNX1_HUMAN (1-453): 0: 702: 100.00
+	Hs
		62529 RFOX3_HUMAN (24-230): 3.58e-37: 139: 19.05		RUNX1_HUMAN (1-453): 0: 702: 100.00
+	Hs
		964316 PABP4_HUMAN (2-265): 2.72e-31: 128: 11.81		RUNX1_HUMAN (1-453): 0: 702: 100.00
+	Hs
		703369 CSTF2_HUMAN (85-177): 1.23e-20: 96.4: 32.26		RUNX1_HUMAN (1-453): 0: 702: 100.00
+	Hs
		964429 CSTFT_HUMAN (84-177): 2.89e-20: 95.3: 30.85		RUNX1_HUMAN (1-453): 0: 702: 100.00
+	Hs
		235804 HNRPQ_HUMAN (4-313): 1.11e-16: 84.2: 13.55		RUNX1_HUMAN (1-453): 0: 702: 100.00