HitPredict

Interactor 1: RU17 (P08621)
U1 small nuclear ribonucleoprotein 70 kDa (U1 snRNP 70 kDa) (U1-70K) (snRNP70)
Gene: SNRNP70

Interactor 2: CUL4B (Q13620)
Cullin-4B (CUL-4B)
Gene: CUL4B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	28225217, 21145461
Identification Methods	proximity labelling technology, affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 437 Hs			1 913
+	Hs
		516507 PABP1_HUMAN (4-361): 2.68e-53: 190: 11.08		CUL4B_HUMAN (1-913): 0: 1184: 100.00
+	Hs
		1031319 PABP4_HUMAN (2-265): 2.72e-31: 128: 11.81		CUL4B_HUMAN (1-913): 0: 1184: 100.00
+	Hs
		703382 CSTF2_HUMAN (85-177): 1.23e-20: 96.4: 32.26		CUL4B_HUMAN (1-913): 0: 1184: 100.00
+	Hs
		516506 PABP1_HUMAN (4-361): 2.68e-53: 190: 11.08		CUL4A_HUMAN (161-913): 0: 955: 81.83
+	Hs
		442141 RU17_HUMAN (1-437): 8.99e-46: 165: 100.00		CUL4A_HUMAN (161-913): 0: 955: 81.83
+	Hs
		1031318 PABP4_HUMAN (2-265): 2.72e-31: 128: 11.81		CUL4A_HUMAN (161-913): 0: 955: 81.83
+	Hs
		516505 PABP1_HUMAN (4-361): 2.68e-53: 190: 11.08		CUL3_HUMAN (186-913): 0: 853: 37.19
+	Hs
		442140 RU17_HUMAN (1-437): 8.99e-46: 165: 100.00		CUL3_HUMAN (186-913): 0: 853: 37.19
+	Hs
		1042136 PPIL4_HUMAN (63-356): 2.16e-35: 138: 17.17		CUL3_HUMAN (186-913): 0: 853: 37.19
+	Hs
		1042933 RBM7_HUMAN (96-357): 1.08e-35: 134: 18.73		CUL3_HUMAN (186-913): 0: 853: 37.19
+	Hs
		1031317 PABP4_HUMAN (2-265): 2.72e-31: 128: 11.81		CUL3_HUMAN (186-913): 0: 853: 37.19
+	Hs
		516503 PABP1_HUMAN (4-361): 2.68e-53: 190: 11.08		CUL1_HUMAN (213-913): 0: 778: 30.16
+	Hs
		442138 RU17_HUMAN (1-437): 8.99e-46: 165: 100.00		CUL1_HUMAN (213-913): 0: 778: 30.16
+	Hs
		516504 PABP1_HUMAN (4-361): 2.68e-53: 190: 11.08		CUL2_HUMAN (205-913): 0: 746: 27.53
+	Hs
		442139 RU17_HUMAN (1-437): 8.99e-46: 165: 100.00		CUL2_HUMAN (205-913): 0: 746: 27.53
+	Hs
		1031315 PABP4_HUMAN (2-265): 2.72e-31: 128: 11.81		CUL1_HUMAN (213-913): 0: 778: 30.16
+	Hs
		1031316 PABP4_HUMAN (2-265): 2.72e-31: 128: 11.81		CUL2_HUMAN (205-913): 0: 746: 27.53
+	Hs
		516626 PABP1_HUMAN (4-361): 2.68e-53: 190: 11.08		CUL5_HUMAN (213-913): 0: 610: 26.23
+	Hs
		442369 RU17_HUMAN (1-437): 8.99e-46: 165: 100.00		CUL5_HUMAN (213-913): 0: 610: 26.23
+	Hs
		1031416 PABP4_HUMAN (2-265): 2.72e-31: 128: 11.81		CUL5_HUMAN (213-913): 0: 610: 26.23