HitPredict

Interactor 1: RU17 (P08621)
U1 small nuclear ribonucleoprotein 70 kDa (U1 snRNP 70 kDa) (U1-70K) (snRNP70)
Gene: SNRNP70

Interactor 2: EZH2 (Q15910)
Histone-lysine N-methyltransferase EZH2 (EC 2.1.1.356) (ENX-1) (Enhancer of zeste homolog 2) (Lysine N-methyltransferase 6)
Gene: EZH2

Species: Homo sapiens

Source: innatedb

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	24457600, 36517590
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 437 Hs			1 746
+	Hs
		516536 PABP1_HUMAN (4-361): 2.68e-53: 190: 11.08		EZH2_HUMAN (1-746): 0: 862: 100.00
+	Hs
		1031345 PABP4_HUMAN (2-265): 2.72e-31: 128: 11.81		EZH2_HUMAN (1-746): 0: 862: 100.00
+	Hs
		963528 TIAR_HUMAN (97-338): 4.83e-20: 93.1: 14.18		EZH2_HUMAN (1-746): 0: 862: 100.00
+	Hs
		235879 HNRPQ_HUMAN (4-313): 1.11e-16: 84.2: 13.55		EZH2_HUMAN (1-746): 0: 862: 100.00
+	Hs
		516645 PABP1_HUMAN (4-361): 2.68e-53: 190: 11.08		NSD1_HUMAN (275-729): 6.24e-90: 311: 15.82
+	Sc
		376833 PABP_YEAST (2-281): 3.47e-29: 121: 12.15		SET2_YEAST (470-733): 1.22e-59: 216: 25.56
+	Hs
		236137 HNRPQ_HUMAN (4-313): 1.11e-16: 84.2: 13.55		SET1B_HUMAN (619-732): 1.38e-18: 93.2: 40.52