HitPredict

Interactor 1: RU17 (P08621)
U1 small nuclear ribonucleoprotein 70 kDa (U1 snRNP 70 kDa) (U1-70K) (snRNP70)
Gene: SNRNP70

Interactor 2: ZC3H8 (Q8N5P1)
Zinc finger CCCH domain-containing protein 8
Gene: ZC3H8

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	29802200
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RRM_1~zf-CCCH
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 437 Hs			1 291
+	Hs
		235952 HNRPQ_HUMAN (4-313): 1.11e-16: 84.2: 13.55		ZC3H8_HUMAN (1-291): 4.74e-129: 370: 100.00
+	Hs
		442597 RU17_HUMAN (1-437): 8.99e-46: 165: 100.00		ZC3H4_HUMAN (176-289): 8.98e-38: 143: 47.37
+	Hs
		516684 PABP1_HUMAN (4-361): 2.68e-53: 190: 11.08		MKRN2_HUMAN (194-287): 2.19e-27: 111: 27.37
+	Hs
		1221460 PABP3_HUMAN (4-361): 3.46e-50: 181: 11.86		ZC3H3_HUMAN (105-274): 2.29e-23: 101: 19.81
+	Hs
		256453 PABP1_HUMAN (4-361): 2.68e-53: 190: 11.08		ZC11A_HUMAN (195-268): 4.39e-18: 86: 28.40
+	Hs
		442479 RU17_HUMAN (1-437): 8.99e-46: 165: 100.00		MKRN2_HUMAN (194-287): 2.19e-27: 111: 27.37
+	Hs
		1288624 PABP5_HUMAN (4-350): 4.45e-37: 141: 11.14		MKRN2_HUMAN (194-287): 2.19e-27: 111: 27.37
+	Hs
		516728 PABP1_HUMAN (4-361): 2.68e-53: 190: 11.08		MKRN1_HUMAN (222-271): 4.98e-10: 61.8: 25.46
+	Hs
		256447 RU17_HUMAN (1-437): 8.99e-46: 165: 100.00		ZC11A_HUMAN (195-268): 4.39e-18: 86: 28.40
+	Hs
		1031454 PABP4_HUMAN (2-265): 2.72e-31: 128: 11.81		MKRN2_HUMAN (194-287): 2.19e-27: 111: 27.37
+	Hs
		1031384 PABP4_HUMAN (2-265): 2.72e-31: 128: 11.81		ZC3H3_HUMAN (105-274): 2.29e-23: 101: 19.81
+	Hs
		256559 PABP5_HUMAN (4-350): 4.45e-37: 141: 11.14		ZC11A_HUMAN (195-268): 4.39e-18: 86: 28.40
+	Hs
		442571 RU17_HUMAN (1-437): 8.99e-46: 165: 100.00		MKRN1_HUMAN (222-271): 4.98e-10: 61.8: 25.46
+	Hs
		317806 RU17_HUMAN (1-437): 8.99e-46: 165: 100.00		CPSF4_HUMAN (180-248): 3e-09: 58.7: 20.00
+	Hs
		1288644 PABP5_HUMAN (4-350): 4.45e-37: 141: 11.14		MKRN1_HUMAN (222-271): 4.98e-10: 61.8: 25.46
+	Dm
		1364313 Q9VE52_DROME (90-177): 5.87e-21: 96.4: 31.82		CPSF4_DROME (171-276): 1.83e-25: 104: 20.35
+	Hs
		1031488 PABP4_HUMAN (2-265): 2.72e-31: 128: 11.81		MKRN1_HUMAN (222-271): 4.98e-10: 61.8: 25.46
+	Hs
		317813 CSTF2_HUMAN (85-177): 1.23e-20: 96.4: 32.26		CPSF4_HUMAN (180-248): 3e-09: 58.7: 20.00
+	Hs
		963580 TIAR_HUMAN (97-338): 4.83e-20: 93.1: 14.18		MKRN1_HUMAN (222-271): 4.98e-10: 61.8: 25.46
+	Hs
		317856 CSTFT_HUMAN (84-177): 2.89e-20: 95.3: 30.85		CPSF4_HUMAN (180-248): 3e-09: 58.7: 20.00