HitPredict

Interactor 1: RU17 (P08621)
U1 small nuclear ribonucleoprotein 70 kDa (U1 snRNP 70 kDa) (U1-70K) (snRNP70)
Gene: SNRNP70

Interactor 2: LN28A (Q9H9Z2)
Protein lin-28 homolog A (Lin-28A) (Zinc finger CCHC domain-containing protein 1)
Gene: LIN28A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	24778252
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	CSD~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0003729 - mRNA binding GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 437 Hs			1 209
+	Mm
		665764 PABP1_MOUSE (4-361): 4.42e-53: 189: 11.08		LN28A_MOUSE (1-209): 1.96e-86: 255: 96.65
+	Hs
		516697 PABP1_HUMAN (4-361): 2.68e-53: 190: 11.08		LN28A_HUMAN (1-209): 2.97e-84: 250: 100.00
+	Mm
		1225251 Q99LF8_MOUSE (2-265): 4.87e-30: 124: 12.18		LN28A_MOUSE (1-209): 1.96e-86: 255: 96.65
+	Hs
		1031465 PABP4_HUMAN (2-265): 2.72e-31: 128: 11.81		LN28A_HUMAN (1-209): 2.97e-84: 250: 100.00
+	Hs
		442254 RU17_HUMAN (1-437): 8.99e-46: 165: 100.00		LN28B_HUMAN (11-205): 3.72e-64: 200: 66.67
+	Hs
		474037 PAB4L_HUMAN (7-182): 1.94e-24: 105: 13.56		LN28A_HUMAN (1-209): 2.97e-84: 250: 100.00
+	Hs
		516455 PABP1_HUMAN (4-361): 2.68e-53: 190: 11.08		YBOX1_HUMAN (26-201): 4.67e-34: 125: 21.16
+	Hs
		931406 PABP3_HUMAN (4-361): 3.46e-50: 181: 11.86		YBOX1_HUMAN (26-201): 4.67e-34: 125: 21.16
+	Hs
		474028 PAB4L_HUMAN (7-182): 1.94e-24: 105: 13.56		LN28B_HUMAN (11-205): 3.72e-64: 200: 66.67
+	Hs
		516350 PABP1_HUMAN (4-361): 2.68e-53: 190: 11.08		YBOX3_HUMAN (27-125): 7.51e-30: 115: 34.95
+	Hs
		1288651 PABP5_HUMAN (4-350): 4.45e-37: 141: 11.14		YBOX2_HUMAN (16-199): 1.7e-44: 153: 23.86
+	Hs
		442041 RU17_HUMAN (1-437): 8.99e-46: 165: 100.00		YBOX1_HUMAN (26-201): 4.67e-34: 125: 21.16
+	Hs
		441863 RU17_HUMAN (1-437): 8.99e-46: 165: 100.00		YBOX3_HUMAN (27-125): 7.51e-30: 115: 34.95
+	Hs
		931325 PABP5_HUMAN (4-350): 4.45e-37: 141: 11.14		YBOX1_HUMAN (26-201): 4.67e-34: 125: 21.16
+	Hs
		563174 PABP5_HUMAN (4-350): 4.45e-37: 141: 11.14		YBOX3_HUMAN (27-125): 7.51e-30: 115: 34.95
+	At
		1257878 U1135_ARATH (88-340): 8.8e-52: 179: 33.45		RSZ33_ARATH (115-184): 3.06e-16: 76.9: 22.86
+	Hs
		914823 PABP3_HUMAN (4-361): 3.46e-50: 181: 11.86		CNBP_HUMAN (123-200): 4.23e-16: 74.6: 23.75
+	Hs
		931135 PABP4_HUMAN (2-265): 2.72e-31: 128: 11.81		YBOX1_HUMAN (26-201): 4.67e-34: 125: 21.16
+	Hs
		474013 PAB4L_HUMAN (7-182): 1.94e-24: 105: 13.56		YBOX1_HUMAN (26-201): 4.67e-34: 125: 21.16
+	At
		1163064 CYP59_ARATH (34-383): 3.15e-40: 152: 20.21		RSZ33_ARATH (115-184): 3.06e-16: 76.9: 22.86