HitPredict

Interactor 1: RU17 (P08621)
U1 small nuclear ribonucleoprotein 70 kDa (U1 snRNP 70 kDa) (U1-70K) (snRNP70)
Gene: SNRNP70

Interactor 2: RC3H2 (Q9HBD1)
Roquin-2 (EC 2.3.2.27) (Membrane-associated nucleic acid-binding protein) (RING finger and CCCH-type zinc finger domain-containing protein 2) (RING finger protein 164) (RING-type E3 ubiquitin transferase Roquin-2)
Gene: RC3H2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	30209976
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RRM_1~zf-CCCH
Common GO terms	GO:0003723 - RNA binding GO:0003729 - mRNA binding
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 437 Hs			1 1191
+	Hs
		516698 PABP1_HUMAN (4-361): 2.68e-53: 190: 11.08		RC3H2_HUMAN (1-1191): 0: 1105: 100.00
+	Hs
		1329984 PABP3_HUMAN (4-361): 3.46e-50: 181: 11.86		RC3H2_HUMAN (1-1191): 0: 1105: 100.00
+	Hs
		1288632 PABP5_HUMAN (4-350): 4.45e-37: 141: 11.14		RC3H2_HUMAN (1-1191): 0: 1105: 100.00
+	Hs
		1031467 PABP4_HUMAN (2-265): 2.72e-31: 128: 11.81		RC3H2_HUMAN (1-1191): 0: 1105: 100.00
+	Hs
		680490 TIA1_HUMAN (98-338): 2.21e-18: 88.4: 12.95		RC3H2_HUMAN (1-1191): 0: 1105: 100.00
+	Hs
		236080 HNRPQ_HUMAN (4-313): 1.11e-16: 84.2: 13.55		RC3H2_HUMAN (1-1191): 0: 1105: 100.00
+	Hs
		516550 PABP1_HUMAN (4-361): 2.68e-53: 190: 11.08		RC3H1_HUMAN (1-1108): 0: 788: 49.30
+	Hs
		1136287 PABP3_HUMAN (4-361): 3.46e-50: 181: 11.86		RC3H1_HUMAN (1-1108): 0: 788: 49.30
+	Hs
		442227 RU17_HUMAN (1-437): 8.99e-46: 165: 100.00		RC3H1_HUMAN (1-1108): 0: 788: 49.30
+	Hs
		1136223 PABP5_HUMAN (4-350): 4.45e-37: 141: 11.14		RC3H1_HUMAN (1-1108): 0: 788: 49.30
+	Hs
		1031360 PABP4_HUMAN (2-265): 2.72e-31: 128: 11.81		RC3H1_HUMAN (1-1108): 0: 788: 49.30
+	Hs
		235898 HNRPQ_HUMAN (4-313): 1.11e-16: 84.2: 13.55		RC3H1_HUMAN (1-1108): 0: 788: 49.30
+	Hs
		516595 PABP1_HUMAN (4-361): 2.68e-53: 190: 11.08		KMT2C_HUMAN (351-895): 4.49e-14: 79.7: 9.35
+	Hs
		325826 PPIL4_HUMAN (63-356): 2.16e-35: 138: 17.17		LATS1_HUMAN (518-1066): 1.1e-09: 65: 11.05
+	Ce
		107192 SIG7_CAEEL (30-257): 1.69e-32: 129: 24.12		RPB1_CAEEL (710-1030): 1.22e-11: 71.6: 9.62
+	Hs
		963553 TIAR_HUMAN (97-338): 4.83e-20: 93.1: 14.18		CBP_HUMAN (556-893): 1.74e-09: 64.6: 9.77
+	Hs
		1270785 RBM24_HUMAN (98-177): 1.49e-15: 77.5: 31.25		CBP_HUMAN (556-893): 1.74e-09: 64.6: 9.77