HitPredict

Interactor 1: RU17 (P08621)
U1 small nuclear ribonucleoprotein 70 kDa (U1 snRNP 70 kDa) (U1-70K) (snRNP70)
Gene: SNRNP70

Interactor 2: STRAP (Q9Y3F4)
Serine-threonine kinase receptor-associated protein (MAP activator with WD repeats) (UNR-interacting protein) (WD-40 repeat protein PT-WD)
Gene: STRAP

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	24981860, 29802200, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0003729 - mRNA binding GO:0005634 - nucleus
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 437 Hs			1 350
+	Dm
		1129076 SET1_DROME (53-387): 1.25e-41: 160: 20.59		WDS_DROME (1-173): 4.41e-44: 157: 21.55
+	Hs
		442381 RU17_HUMAN (1-437): 8.99e-46: 165: 100.00		SNR40_HUMAN (1-126): 8.45e-28: 113: 22.96
+	Hs
		516438 PABP1_HUMAN (4-361): 2.68e-53: 190: 11.08		WDR5_HUMAN (253-346): 5.02e-18: 85.4: 18.09
+	Hs
		442202 RU17_HUMAN (1-437): 8.99e-46: 165: 100.00		SMU1_HUMAN (26-293): 7.19e-16: 80.5: 26.87
+	Hs
		1259857 PPIL4_HUMAN (63-356): 2.16e-35: 138: 17.17		FBXW7_HUMAN (209-344): 2.04e-24: 106: 15.94
+	Hs
		196943 RU17_HUMAN (1-437): 8.99e-46: 165: 100.00		PRP4_HUMAN (263-347): 2.41e-15: 78.9: 16.47
+	Sc
		376807 PABP_YEAST (2-281): 3.47e-29: 121: 12.15		EIF3I_YEAST (11-291): 1.3e-23: 101: 27.85
+	Hs
		903196 PABP4_HUMAN (2-265): 2.72e-31: 128: 11.81		WDR5_HUMAN (253-346): 5.02e-18: 85.4: 18.09
+	Hs
		235994 HNRPQ_HUMAN (4-313): 1.11e-16: 84.2: 13.55		FBXW7_HUMAN (209-344): 2.04e-24: 106: 15.94
+	Hs
		235781 HNRPQ_HUMAN (4-313): 1.11e-16: 84.2: 13.55		WDR5_HUMAN (253-346): 5.02e-18: 85.4: 18.09