HitPredict

Interactor 1: RB (P06400)
Retinoblastoma-associated protein (p105-Rb) (p110-RB1) (pRb) (Rb) (pp110)
Gene: RB1

Interactor 2: NFIX (Q14938)
Nuclear factor 1 X-type (NF1-X) (Nuclear factor 1/X) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/X) (NF-I/X) (NFI-X) (TGGCA-binding protein)
Gene: NFIX

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	11896613, 39617063
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000785 - chromatin GO:0005634 - nucleus GO:0006366 - transcription by RNA polymerase II GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 928 Hs			1 502
+	Hs
		442688 RB_HUMAN (1-928): 0: 1323: 100.00		NFIA_HUMAN (1-502): 1.45e-118: 359: 66.47
+	Hs
		442548 RB_HUMAN (1-928): 0: 1323: 100.00		NFIC_HUMAN (3-502): 4.99e-114: 348: 53.43
+	Hs
		142788 RB_HUMAN (1-928): 0: 1323: 100.00		NFIB_HUMAN (1-419): 3.83e-101: 311: 58.69