HitPredict

Interactor 1: HCK (P08631)
Tyrosine-protein kinase HCK (EC 2.7.10.2) (Hematopoietic cell kinase) (Hemopoietic cell kinase) (p59-HCK/p60-HCK) (p59Hck) (p61Hck)
Gene: HCK

Interactor 2: BCR (P11274)
Breakpoint cluster region protein (EC 2.7.11.1) (Renal carcinoma antigen NY-REN-26)
Gene: BCR

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 1.00 0.754

The method score is based on:

Property Details
Experiments 12592324, 10849448
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains C2~SH2, RhoGEF~SH3_1
Common GO terms GO:0004713 - protein tyrosine kinase activity
GO:0005524 - ATP binding
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0006468 - protein phosphorylation
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 526
Hs

1 1271
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+ Ce

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024