HitPredict

Interactor 1: HCK (P08631)
Tyrosine-protein kinase HCK (EC 2.7.10.2) (Hematopoietic cell kinase) (Hemopoietic cell kinase) (p59-HCK/p60-HCK) (p59Hck) (p61Hck)
Gene: HCK

Interactor 2: H90B2 (Q58FF8)
Putative heat shock protein HSP 90-beta 2 (Heat shock protein 90-beta b) (Heat shock protein 90Bb)
Gene: HSP90AB2P

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	unassigned2173
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 526 Hs			1 381
+	Hs
		442841 HCK_HUMAN (1-526): 0: 635: 100.00		H90B3_HUMAN (1-381): 8.64e-116: 350: 59.04
+	Hs
		411751 LCK_HUMAN (23-526): 0: 581: 64.89		H90B3_HUMAN (1-381): 8.64e-116: 350: 59.04
+	Hs
		433379 YES_HUMAN (1-524): 0: 570: 56.77		H90B3_HUMAN (1-381): 8.64e-116: 350: 59.04
+	Hs
		412223 FYN_HUMAN (22-524): 0: 564: 57.79		H90B3_HUMAN (1-381): 8.64e-116: 350: 59.04
+	Hs
		433381 YES_HUMAN (1-524): 0: 570: 56.77		HS904_HUMAN (57-381): 4.72e-80: 253: 37.27
+	Hs
		412224 FYN_HUMAN (22-524): 0: 564: 57.79		HS904_HUMAN (57-381): 4.72e-80: 253: 37.27
+	Hs
		411978 FYN_HUMAN (22-524): 0: 564: 57.79		ENPL_HUMAN (185-381): 1.31e-65: 224: 34.98
+	Hs
		437817 HCK_HUMAN (1-526): 0: 635: 100.00		HS90B_HUMAN (109-251): 8.66e-32: 128: 87.41
+	Hs
		433380 YES_HUMAN (1-524): 0: 570: 56.77		HS905_HUMAN (108-355): 1.06e-55: 187: 60.08
+	Hs
		431445 HCK_HUMAN (1-526): 0: 635: 100.00		HS90A_HUMAN (87-251): 2.97e-26: 112: 61.54
+	Hs
		437847 SRC_HUMAN (1-524): 0: 582: 54.51		HS90B_HUMAN (109-251): 8.66e-32: 128: 87.41
+	Hs
		411556 LCK_HUMAN (23-526): 0: 581: 64.89		HS90B_HUMAN (109-251): 8.66e-32: 128: 87.41
+	Hs
		433378 YES_HUMAN (1-524): 0: 570: 56.77		H90B4_HUMAN (109-247): 1.76e-32: 129: 75.54
+	Hs
		433218 YES_HUMAN (1-524): 0: 570: 56.77		HS90B_HUMAN (109-251): 8.66e-32: 128: 87.41
+	Hs
		431481 SRC_HUMAN (1-524): 0: 582: 54.51		HS90A_HUMAN (87-251): 2.97e-26: 112: 61.54
+	Hs
		411551 LCK_HUMAN (23-526): 0: 581: 64.89		HS90A_HUMAN (87-251): 2.97e-26: 112: 61.54
+	Hs
		412222 FYN_HUMAN (22-524): 0: 564: 57.79		H90B4_HUMAN (109-247): 1.76e-32: 129: 75.54
+	Hs
		411949 FYN_HUMAN (22-524): 0: 564: 57.79		HS90B_HUMAN (109-251): 8.66e-32: 128: 87.41
+	Hs
		431433 YES_HUMAN (1-524): 0: 570: 56.77		HS90A_HUMAN (87-251): 2.97e-26: 112: 61.54
+	Hs
		411945 FYN_HUMAN (22-524): 0: 564: 57.79		HS90A_HUMAN (87-251): 2.97e-26: 112: 61.54