HitPredict

Interactor 1: ITA5 (P08648)
Integrin alpha-5 (CD49 antigen-like family member E) (Fibronectin receptor subunit alpha) (Integrin alpha-F) (VLA-5) (CD antigen CD49e) [Cleaved into: Integrin alpha-5 heavy chain; Integrin alpha-5 light chain]
Gene: ITGA5

Interactor 2: LEG12 (Q96DT0)
Galectin-12 (Gal-12) (Galectin-related inhibitor of proliferation)
Gene: LGALS12

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1049 Hs			1 336
+	Hs
		443032 ITA5_HUMAN (1-1049): 0: 1230: 100.00		LEG3_HUMAN (188-333): 3.97e-45: 156: 22.37
+	Hs
		119100 ITA5_HUMAN (1-1049): 0: 1230: 100.00		LEG9_HUMAN (6-181): 5.5e-41: 148: 29.61
+	Hs
		121084 ITA5_HUMAN (1-1049): 0: 1230: 100.00		LEG8_HUMAN (13-180): 6.04e-36: 134: 27.06
+	Hs
		443022 ITA5_HUMAN (1-1049): 0: 1230: 100.00		LEG1_HUMAN (219-334): 2.33e-34: 124: 22.58
+	Hs
		449225 ITA8_HUMAN (18-1049): 0: 1121: 45.01		LEG1_HUMAN (219-334): 2.33e-34: 124: 22.58
+	Hs
		121078 ITAV_HUMAN (39-1028): 0: 1084: 45.89		LEG8_HUMAN (13-180): 6.04e-36: 134: 27.06
+	Hs
		419138 ITAV_HUMAN (39-1028): 0: 1084: 45.89		LEG1_HUMAN (219-334): 2.33e-34: 124: 22.58
+	Mm
		139224 ITA2B_MOUSE (14-1032): 0: 946: 37.03		LEG9_MOUSE (6-181): 2.45e-43: 154: 30.17
+	Hs
		119131 ITA4_HUMAN (18-1039): 0: 917: 24.62		LEG9_HUMAN (6-181): 5.5e-41: 148: 29.61
+	Hs
		121095 ITA4_HUMAN (18-1039): 0: 917: 24.62		LEG8_HUMAN (13-180): 6.04e-36: 134: 27.06
+	Hs
		449172 ITA4_HUMAN (18-1039): 0: 917: 24.62		LEG1_HUMAN (219-334): 2.33e-34: 124: 22.58
+	Hs
		121107 ITA6_HUMAN (28-1045): 0: 904: 24.71		LEG8_HUMAN (13-180): 6.04e-36: 134: 27.06
+	Hs
		121150 ITA7_HUMAN (17-1045): 0: 894: 26.21		LEG8_HUMAN (13-180): 6.04e-36: 134: 27.06
+	Hs
		449190 ITA6_HUMAN (28-1045): 0: 904: 24.71		LEG1_HUMAN (219-334): 2.33e-34: 124: 22.58
+	Hs
		449259 ITA9_HUMAN (38-1042): 0: 899: 26.33		LEG1_HUMAN (219-334): 2.33e-34: 124: 22.58
+	Hs
		449257 ITA7_HUMAN (17-1045): 0: 894: 26.21		LEG1_HUMAN (219-334): 2.33e-34: 124: 22.58
+	Hs
		121110 ITA3_HUMAN (18-1042): 0: 804: 25.41		LEG8_HUMAN (13-180): 6.04e-36: 134: 27.06
+	Hs
		449196 ITA3_HUMAN (18-1042): 0: 804: 25.41		LEG1_HUMAN (219-334): 2.33e-34: 124: 22.58
+	Hs
		121135 ITA1_HUMAN (19-194): 1.47e-36: 152: 27.37		LEG8_HUMAN (13-180): 6.04e-36: 134: 27.06
+	Hs
		449228 ITA1_HUMAN (19-194): 1.47e-36: 152: 27.37		LEG1_HUMAN (219-334): 2.33e-34: 124: 22.58