HitPredict

Interactor 1: NFIC (P08651)
Nuclear factor 1 C-type (NF1-C) (Nuclear factor 1/C) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/C) (NF-I/C) (NFI-C) (TGGCA-binding protein)
Gene: NFIC

Interactor 2: NFIC (P08651)
Nuclear factor 1 C-type (NF1-C) (Nuclear factor 1/C) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/C) (NF-I/C) (NFI-C) (TGGCA-binding protein)
Gene: NFIC

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.58 1.00 0.768

The method score is based on:

Property Details
Experiments 28205554, 25258084
Identification Methods fluorescent resonance energy transfer, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains MH1~MH1
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific
and 9 others

more...
Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 508
Hs

1 508
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Last updated: 15 Jul 2024