HitPredict

Interactor 1: VIME (P08670)
Vimentin
Gene: VIM

Interactor 2: LMNB1 (P20700)
Lamin-B1
Gene: LMNB1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	1.00	0.789

Property	Details
Experiments	11441066, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Filament~Filament
Common GO terms	GO:0005200 - structural constituent of cytoskeleton GO:0016363 - nuclear matrix
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 466 Hs			1 586
+	Hs
		569099 DESM_HUMAN (9-465): 6.68e-138: 406: 62.20		K2C73_HUMAN (2-391): 1.07e-53: 193: 19.70
+	Hs
		318775 DESM_HUMAN (9-465): 6.68e-138: 406: 62.20		K2C75_HUMAN (4-391): 1.8e-50: 184: 20.61
+	Hs
		409072 K2C8_HUMAN (79-461): 3.38e-139: 410: 35.51		K1H2_HUMAN (75-388): 3.56e-46: 170: 21.59
+	Hs
		318786 PERI_HUMAN (7-462): 7.65e-130: 385: 58.08		K2C75_HUMAN (4-391): 1.8e-50: 184: 20.61
+	Hs
		408979 K2C8_HUMAN (79-461): 3.38e-139: 410: 35.51		VIME_HUMAN (28-390): 5.22e-30: 125: 28.65
+	Hs
		318768 VIME_HUMAN (14-466): 9.64e-116: 349: 100.00		K2C75_HUMAN (4-391): 1.8e-50: 184: 20.61
+	Hs
		443316 DESM_HUMAN (9-465): 6.68e-138: 406: 62.20		VIME_HUMAN (28-390): 5.22e-30: 125: 28.65
+	Hs
		408991 K2C8_HUMAN (79-461): 3.38e-139: 410: 35.51		GFAP_HUMAN (6-418): 1.55e-27: 117: 29.23
+	Hs
		569045 DESM_HUMAN (9-465): 6.68e-138: 406: 62.20		DESM_HUMAN (28-390): 1.04e-28: 121: 31.13
+	Hs
		535322 DESM_HUMAN (9-465): 6.68e-138: 406: 62.20		GFAP_HUMAN (6-418): 1.55e-27: 117: 29.23
+	Hs
		280943 K2C8_HUMAN (79-461): 3.38e-139: 410: 35.51		KRT38_HUMAN (31-407): 1.45e-25: 111: 28.23
+	Hs
		409022 K2C8_HUMAN (79-461): 3.38e-139: 410: 35.51		PERI_HUMAN (28-390): 1.66e-25: 111: 30.79
+	Hs
		569056 DESM_HUMAN (9-465): 6.68e-138: 406: 62.20		PERI_HUMAN (28-390): 1.66e-25: 111: 30.79
+	Hs
		443295 GFAP_HUMAN (80-465): 2.56e-132: 390: 61.40		VIME_HUMAN (28-390): 5.22e-30: 125: 28.65
+	Hs
		443379 PERI_HUMAN (7-462): 7.65e-130: 385: 58.08		VIME_HUMAN (28-390): 5.22e-30: 125: 28.65
+	Hs
		535314 GFAP_HUMAN (80-465): 2.56e-132: 390: 61.40		GFAP_HUMAN (6-418): 1.55e-27: 117: 29.23
+	Hs
		535339 GFAP_HUMAN (80-465): 2.56e-132: 390: 61.40		PERI_HUMAN (28-390): 1.66e-25: 111: 30.79