HitPredict

Interactor 1: VIME (P08670)
Vimentin
Gene: VIM

Interactor 2: SQSTM (Q13501)
Sequestosome-1 (EBI3-associated protein of 60 kDa) (EBIAP) (p60) (Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa) (Ubiquitin-binding protein p62)
Gene: SQSTM1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	28968743, 20562859
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 466 Hs			1 440
+	Hs
		409063 K2C8_HUMAN (79-461): 3.38e-139: 410: 35.51		SQSTM_HUMAN (1-440): 0: 760: 100.00
+	Mm
		589635 VIME_MOUSE (14-466): 1.1e-109: 334: 97.35		SQSTM_MOUSE (1-440): 0: 731: 90.72
+	Hs
		1036608 AINX_HUMAN (82-422): 6.14e-97: 302: 54.91		SQSTM_HUMAN (1-440): 0: 760: 100.00
+	Hs
		1036707 K2C73_HUMAN (5-414): 3.57e-91: 289: 32.10		SQSTM_HUMAN (1-440): 0: 760: 100.00
+	Hs
		422388 NFM_HUMAN (9-412): 5.26e-84: 278: 46.44		SQSTM_HUMAN (1-440): 0: 760: 100.00
+	Hs
		580128 K2C4_HUMAN (4-430): 2.28e-79: 257: 30.70		SQSTM_HUMAN (1-440): 0: 760: 100.00
+	Hs
		409074 K2C8_HUMAN (79-461): 3.38e-139: 410: 35.51		NBR1_HUMAN (80-184): 5.95e-10: 63.6: 24.78
+	Hs
		319691 K2C6B_HUMAN (68-430): 5.13e-73: 242: 33.42		HERC2_HUMAN (120-197): 2.6e-12: 71.3: 32.50
+	Hs
		319759 K2C6C_HUMAN (68-430): 9.35e-73: 241: 33.70		HERC2_HUMAN (120-197): 2.6e-12: 71.3: 32.50