HitPredict

Interactor 1: VIME (P08670)
Vimentin
Gene: VIM

Interactor 2: SH3G1 (Q99961)
Endophilin-A2 (EEN fusion partner of MLL) (Endophilin-2) (Extra eleven-nineteen leukemia fusion gene protein) (EEN) (SH3 domain protein 2B) (SH3 domain-containing GRB2-like protein 1)
Gene: SH3GL1

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.600

Property	Details
Experiments	34079125, 21900206
Identification Methods	proximity labelling technology, two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 466 Hs			1 368
+	Hs
		443759 VIME_HUMAN (14-466): 9.64e-116: 349: 100.00		SH3G3_HUMAN (1-368): 1.31e-87: 270: 66.30
+	Hs
		569047 DESM_HUMAN (9-465): 6.68e-138: 406: 62.20		NEBU_HUMAN (7-363): 5.75e-36: 141: 16.13
+	Hs
		569077 DESM_HUMAN (9-465): 6.68e-138: 406: 62.20		SPTN1_HUMAN (4-365): 1.47e-33: 134: 15.82
+	Hs
		535531 GFAP_HUMAN (80-465): 2.56e-132: 390: 61.40		SH3Y1_HUMAN (230-362): 4.51e-28: 114: 32.41
+	Hs
		443514 VIME_HUMAN (14-466): 9.64e-116: 349: 100.00		SRC8_HUMAN (35-362): 1.55e-37: 143: 12.16
+	Hs
		443328 VIME_HUMAN (14-466): 9.64e-116: 349: 100.00		NEBU_HUMAN (7-363): 5.75e-36: 141: 16.13
+	Hs
		443504 VIME_HUMAN (14-466): 9.64e-116: 349: 100.00		SPTN1_HUMAN (4-365): 1.47e-33: 134: 15.82
+	Hs
		409046 K2C8_HUMAN (79-461): 3.38e-139: 410: 35.51		GRB2_HUMAN (311-367): 1.59e-11: 65.2: 41.38
+	Hs
		781978 PERI_HUMAN (7-462): 7.65e-130: 385: 58.08		SRBS1_HUMAN (235-363): 3.59e-15: 79.2: 25.95
+	Hs
		443728 VIME_HUMAN (14-466): 9.64e-116: 349: 100.00		SH3Y1_HUMAN (230-362): 4.51e-28: 114: 32.41
+	Hs
		535366 GFAP_HUMAN (80-465): 2.56e-132: 390: 61.40		GRB2_HUMAN (311-367): 1.59e-11: 65.2: 41.38
+	Hs
		443774 VIME_HUMAN (14-466): 9.64e-116: 349: 100.00		SRBS1_HUMAN (235-363): 3.59e-15: 79.2: 25.95
+	Hs
		422392 NFM_HUMAN (9-412): 5.26e-84: 278: 46.44		SRC8_HUMAN (35-362): 1.55e-37: 143: 12.16
+	Hs
		443451 VIME_HUMAN (14-466): 9.64e-116: 349: 100.00		GRB2_HUMAN (311-367): 1.59e-11: 65.2: 41.38
+	Hs
		422175 NFL_HUMAN (82-413): 4.58e-87: 278: 51.80		SPTN1_HUMAN (4-365): 1.47e-33: 134: 15.82
+	Hs
		924679 K2C73_HUMAN (5-414): 3.57e-91: 289: 32.10		GRB2_HUMAN (311-367): 1.59e-11: 65.2: 41.38
+	Hs
		924469 KRT83_HUMAN (5-418): 1.39e-91: 288: 31.34		GRB2_HUMAN (311-367): 1.59e-11: 65.2: 41.38
+	Hs
		924470 KRT85_HUMAN (3-418): 1.66e-91: 288: 32.32		GRB2_HUMAN (311-367): 1.59e-11: 65.2: 41.38
+	Hs
		924576 KRT81_HUMAN (4-418): 4.08e-91: 287: 31.74		GRB2_HUMAN (311-367): 1.59e-11: 65.2: 41.38
+	Hs
		213936 KRT86_HUMAN (4-418): 5.74e-90: 284: 31.74		GRB2_HUMAN (311-367): 1.59e-11: 65.2: 41.38