HitPredict

Interactor 1: VIME (P08670)
Vimentin
Gene: VIM

Interactor 2: SH3G3 (Q99963)
Endophilin-A3 (EEN-B2) (Endophilin-3) (SH3 domain protein 2C) (SH3 domain-containing GRB2-like protein 3)
Gene: SH3GL3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.43	0.60	0.508

Property	Details
Experiments	15383276
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 466 Hs			1 347
+	Hs
		443758 VIME_HUMAN (14-466): 9.64e-116: 349: 100.00		SH3G1_HUMAN (1-347): 7.8e-80: 249: 66.30
+	Hs
		569047 DESM_HUMAN (9-465): 6.68e-138: 406: 62.20		NEBU_HUMAN (7-342): 2.57e-37: 144: 16.06
+	Hs
		535531 GFAP_HUMAN (80-465): 2.56e-132: 390: 61.40		SH3Y1_HUMAN (139-341): 5.08e-38: 140: 19.73
+	Hs
		443514 VIME_HUMAN (14-466): 9.64e-116: 349: 100.00		SRC8_HUMAN (7-343): 2.64e-50: 177: 14.49
+	Hs
		443328 VIME_HUMAN (14-466): 9.64e-116: 349: 100.00		NEBU_HUMAN (7-342): 2.57e-37: 144: 16.06
+	Hs
		443728 VIME_HUMAN (14-466): 9.64e-116: 349: 100.00		SH3Y1_HUMAN (139-341): 5.08e-38: 140: 19.73
+	Hs
		409046 K2C8_HUMAN (79-461): 3.38e-139: 410: 35.51		GRB2_HUMAN (290-346): 9.93e-12: 65.5: 41.38
+	Hs
		569085 DESM_HUMAN (9-465): 6.68e-138: 406: 62.20		ITSN1_HUMAN (253-341): 7.42e-12: 68.9: 23.60
+	Hs
		781978 PERI_HUMAN (7-462): 7.65e-130: 385: 58.08		SRBS1_HUMAN (169-342): 1.13e-13: 74.1: 17.65
+	Hs
		535403 GFAP_HUMAN (80-465): 2.56e-132: 390: 61.40		ITSN1_HUMAN (253-341): 7.42e-12: 68.9: 23.60
+	Hs
		535366 GFAP_HUMAN (80-465): 2.56e-132: 390: 61.40		GRB2_HUMAN (290-346): 9.93e-12: 65.5: 41.38
+	Hs
		781911 PERI_HUMAN (7-462): 7.65e-130: 385: 58.08		SH319_HUMAN (291-342): 6.81e-09: 59.3: 48.08
+	Hs
		443774 VIME_HUMAN (14-466): 9.64e-116: 349: 100.00		SRBS1_HUMAN (169-342): 1.13e-13: 74.1: 17.65
+	Hs
		443451 VIME_HUMAN (14-466): 9.64e-116: 349: 100.00		GRB2_HUMAN (290-346): 9.93e-12: 65.5: 41.38
+	Hs
		924679 K2C73_HUMAN (5-414): 3.57e-91: 289: 32.10		GRB2_HUMAN (290-346): 9.93e-12: 65.5: 41.38
+	Hs
		924469 KRT83_HUMAN (5-418): 1.39e-91: 288: 31.34		GRB2_HUMAN (290-346): 9.93e-12: 65.5: 41.38
+	Hs
		924470 KRT85_HUMAN (3-418): 1.66e-91: 288: 32.32		GRB2_HUMAN (290-346): 9.93e-12: 65.5: 41.38
+	Hs
		924576 KRT81_HUMAN (4-418): 4.08e-91: 287: 31.74		GRB2_HUMAN (290-346): 9.93e-12: 65.5: 41.38
+	Hs
		213936 KRT86_HUMAN (4-418): 5.74e-90: 284: 31.74		GRB2_HUMAN (290-346): 9.93e-12: 65.5: 41.38
+	Hs
		422187 NFL_HUMAN (82-413): 4.58e-87: 278: 51.80		ITSN1_HUMAN (253-341): 7.42e-12: 68.9: 23.60