HitPredict

Interactor 1: VIME (P08670)
Vimentin
Gene: VIM

Interactor 2: PINK1 (Q9BXM7)
Serine/threonine-protein kinase PINK1, mitochondrial (EC 2.7.11.1) (BRPK) (PTEN-induced putative kinase protein 1)
Gene: PINK1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	31300519, 33961781, 23885119
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005856 - cytoskeleton GO:0030424 - axon
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 466 Hs			1 581
+	Hs
		535333 GFAP_HUMAN (80-465): 2.56e-132: 390: 61.40		AKT1_HUMAN (115-573): 2.58e-118: 360: 12.89
+	Hs
		443354 VIME_HUMAN (14-466): 9.64e-116: 349: 100.00		AKT1_HUMAN (115-573): 2.58e-118: 360: 12.89
+	Hs
		443355 VIME_HUMAN (14-466): 9.64e-116: 349: 100.00		AKT2_HUMAN (115-573): 1.5e-117: 358: 12.66
+	Mm
		589625 VIME_MOUSE (14-466): 1.1e-109: 334: 97.35		KPCZ_MOUSE (54-568): 1.12e-116: 360: 13.52
+	Hs
		443315 VIME_HUMAN (14-466): 9.64e-116: 349: 100.00		KAPCA_HUMAN (173-567): 1.06e-110: 336: 13.89
+	Hs
		443885 VIME_HUMAN (14-466): 9.64e-116: 349: 100.00		KCC2A_HUMAN (221-538): 5.11e-82: 266: 20.62
+	Hs
		422343 NFM_HUMAN (9-412): 5.26e-84: 278: 46.44		KAPCA_HUMAN (173-567): 1.06e-110: 336: 13.89
+	Hs
		1055200 K1H2_HUMAN (5-417): 2.97e-76: 247: 26.44		AKT3_HUMAN (110-573): 2.43e-120: 365: 13.88
+	Hs
		681844 K1H2_HUMAN (5-417): 2.97e-76: 247: 26.44		AKT1_HUMAN (115-573): 2.58e-118: 360: 12.89
+	Hs
		1081767 AINX_HUMAN (82-422): 6.14e-97: 302: 54.91		KCC2A_HUMAN (221-538): 5.11e-82: 266: 20.62
+	Hs
		318906 K2C75_HUMAN (6-422): 9.96e-85: 272: 32.51		KCC2A_HUMAN (221-538): 5.11e-82: 266: 20.62
+	Hs
		213943 KRT86_HUMAN (4-418): 5.74e-90: 284: 31.74		KCC2B_HUMAN (267-505): 2.71e-45: 171: 25.31