HitPredict

Interactor 1: BTUC (P06609)
Vitamin B12 import system permease protein BtuC
Gene: BTUC

Interactor 2: BTUD (P06611)
Vitamin B12 import ATP-binding protein BtuD (EC 7.6.2.8) (Vitamin B12-transporting ATPase)
Gene: BTUD

Species: Escherichia coli K-12

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.85 0.90 0.879

The method score is based on:

Property Details
Experiments 12004122, 20173761, 25402482, 19101549, 22569249
Identification Methods x-ray crystallography, pull down, molecular sieving
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains ABC_tran~FecCD
Common GO terms GO:0015420 - ABC-type vitamin B12 transporter activity
GO:0015889 - cobalamin transport
GO:0016020 - membrane
GO:0043190 - ATP-binding cassette (ABC) transporter complex
GO:1990191 - cobalamin transport complex
and 1 others

more...
Homologous interactions 0

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Last updated: 11Aug2025