HitPredict

Interactor 1: K1C19 (P08727)
Keratin, type I cytoskeletal 19 (Cytokeratin-19) (CK-19) (Keratin-19) (K19)
Gene: KRT19

Interactor 2: CFTR (P13569)
Cystic fibrosis transmembrane conductance regulator (CFTR) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (EC 5.6.1.6) (cAMP-dependent chloride channel)
Gene: CFTR

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31324722
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 400 Hs			1 1480
+	Hs
		359298 K1C14_HUMAN (78-391): 5.81e-143: 416: 70.38		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		529151 K1H1_HUMAN (35-397): 1.31e-141: 411: 50.55		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		528449 K1C13_HUMAN (74-388): 7.1e-141: 410: 70.57		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		444998 K1C16_HUMAN (76-397): 5.27e-140: 409: 70.19		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		529011 K1C17_HUMAN (28-393): 1.38e-139: 406: 67.76		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		529614 K1C12_HUMAN (74-387): 1.09e-124: 370: 66.04		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		528448 K1C10_HUMAN (75-385): 1.75e-120: 363: 65.29		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		529118 KT33B_HUMAN (73-388): 2.88e-120: 356: 56.33		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		280490 KT33A_HUMAN (73-388): 1.2e-119: 354: 56.65		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		280518 KRT34_HUMAN (73-388): 2.74e-118: 351: 55.06		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		529780 KRT84_HUMAN (40-400): 2.11e-99: 309: 27.07		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		529119 KRT81_HUMAN (1-400): 7.27e-98: 302: 26.19		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		213928 KRT86_HUMAN (1-400): 5.8e-97: 299: 26.43		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		528963 KRT85_HUMAN (1-400): 1.25e-94: 294: 27.54		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		318772 K2C75_HUMAN (9-399): 2.51e-89: 281: 26.46		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		529130 K2C72_HUMAN (3-394): 7.72e-82: 261: 22.22		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		529503 KRT35_HUMAN (1-398): 2.25e-81: 258: 47.71		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		380440 K2C6B_HUMAN (47-399): 3.73e-79: 255: 24.79		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		528450 K2C5_HUMAN (47-399): 1.07e-78: 255: 25.35		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		528760 K2C6C_HUMAN (47-399): 4.02e-79: 255: 24.79		CFTR_HUMAN (1-1480): 0: 1031: 100.00