HitPredict

Interactor 1: K1C19 (P08727)
Keratin, type I cytoskeletal 19 (Cytokeratin-19) (CK-19) (Keratin-19) (K19)
Gene: KRT19

Interactor 2: APC (P25054)
Adenomatous polyposis coli protein (Protein APC) (Deleted in polyposis 2.5)
Gene: APC

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.614

Property	Details
Experiments	34079125, 20936779
Identification Methods	proximity labelling technology, two hybrid, two hybrid pooling approach
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 400 Hs			1 2843
+	Hs
		359304 K1C14_HUMAN (78-391): 5.81e-143: 416: 70.38		APC_HUMAN (1-2843): 0: 1316: 100.00
+	Hs
		579993 K1C15_HUMAN (79-388): 4.51e-142: 414: 71.70		APC_HUMAN (1-2843): 0: 1316: 100.00
+	Hs
		531447 K1C13_HUMAN (74-388): 7.1e-141: 410: 70.57		APC_HUMAN (1-2843): 0: 1316: 100.00
+	Hs
		626105 K1C17_HUMAN (28-393): 1.38e-139: 406: 67.76		APC_HUMAN (1-2843): 0: 1316: 100.00
+	Hs
		531535 K2C5_HUMAN (47-399): 1.07e-78: 255: 25.35		APC_HUMAN (1-2843): 0: 1316: 100.00
+	Hs
		1205250 K2C73_HUMAN (3-394): 1.09e-97: 303: 24.62		CIC_HUMAN (722-2643): 2.1e-17: 92.4: 7.79