HitPredict

Interactor 1: GNAI3 (P08753)
Guanine nucleotide-binding protein G(i) subunit alpha-3 (G(i) alpha-3)
Gene: GNAI3

Interactor 2: AA3R (P28647)
Adenosine receptor A3 (TGPCR1)
Gene: Adora3

Species: Rattus norvegicus

Source: dip

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	7622506
Identification Methods	coimmunoprecipitation, experimental interaction detection
Interaction Type	physical association

Property	Details
Interacting Pfam domains	7tm_1~G-alpha
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 354 Rn			1 320
+	Hs
		429011 GNAI1_HUMAN (1-354): 7.52e-178: 499: 93.50		ADRB2_HUMAN (4-305): 2.36e-72: 230: 24.54
+	Hs
		391337 GNAI2_HUMAN (1-354): 7.34e-174: 489: 85.35		AA1R_HUMAN (7-319): 7.4e-76: 237: 46.27
+	Hs
		428884 GNAI3_HUMAN (1-354): 6.3e-175: 491: 98.59		ADRB2_HUMAN (4-305): 2.36e-72: 230: 24.54
+	Hs
		391305 GNAI2_HUMAN (1-354): 7.34e-174: 489: 85.35		ADRB2_HUMAN (4-305): 2.36e-72: 230: 24.54
+	Hs
		926680 GNAI1_HUMAN (1-354): 7.52e-178: 499: 93.50		MTR1L_HUMAN (2-305): 5.73e-64: 214: 18.65
+	Rn
		391301 GNAI2_RAT (1-354): 4.32e-173: 486: 85.07		AA3R_RAT (1-320): 3.48e-70: 222: 100.00
+	Hs
		428911 GNAT2_HUMAN (1-354): 1.13e-166: 470: 68.64		ADRB2_HUMAN (4-305): 2.36e-72: 230: 24.54
+	Hs
		391347 GNAI2_HUMAN (1-354): 7.34e-174: 489: 85.35		OPRD_HUMAN (2-319): 7.74e-64: 207: 20.31
+	Hs
		450979 GNAO_HUMAN (1-354): 1.52e-170: 480: 71.27		OPRM_HUMAN (3-320): 1.26e-66: 215: 18.83
+	Hs
		450984 GNAO_HUMAN (1-354): 1.52e-170: 480: 71.27		OPRD_HUMAN (2-319): 7.74e-64: 207: 20.31
+	Bt
		362125 GNAT1_BOVIN (1-354): 7.53e-164: 463: 64.41		OPSD_BOVIN (9-318): 3.89e-64: 207: 16.24
+	Hs
		674835 GNAQ_HUMAN (1-353): 2.59e-161: 457: 50.85		AGTR1_HUMAN (12-319): 4.46e-64: 208: 18.75
+	Hs
		580402 GNAZ_HUMAN (1-353): 1.18e-155: 442: 66.95		DRD5_HUMAN (31-316): 4.06e-66: 216: 22.99
+	Hs
		602214 GNA13_HUMAN (2-353): 2.13e-153: 437: 38.33		DRD5_HUMAN (31-316): 4.06e-66: 216: 22.99
+	Hs
		429010 GNAS2_HUMAN (1-353): 6.03e-140: 404: 38.42		ADRB2_HUMAN (4-305): 2.36e-72: 230: 24.54
+	Hs
		602211 GNAS2_HUMAN (1-353): 6.03e-140: 404: 38.42		DRD5_HUMAN (31-316): 4.06e-66: 216: 22.99
+	Hs
		825681 GNAI1_HUMAN (1-354): 7.52e-178: 499: 93.50		MTR1B_HUMAN (29-301): 2.7e-18: 86.3: 28.87
+	Hs
		444688 GNAI3_HUMAN (1-354): 6.3e-175: 491: 98.59		MTR1B_HUMAN (29-301): 2.7e-18: 86.3: 28.87
+	Hs
		391355 GNAI2_HUMAN (1-354): 7.34e-174: 489: 85.35		MTR1B_HUMAN (29-301): 2.7e-18: 86.3: 28.87
+	Hs
		825680 GNAS2_HUMAN (1-353): 6.03e-140: 404: 38.42		MTR1B_HUMAN (29-301): 2.7e-18: 86.3: 28.87