Interactor 1: GNAI3 (P08754)
Guanine nucleotide-binding protein G(i) subunit alpha-3 (G(i) alpha-3)
Gene: GNAI3
Interactor 2: S1PR1 (P21453)
Sphingosine 1-phosphate receptor 1 (S1P receptor 1) (S1P1) (Endothelial differentiation G-protein coupled receptor 1) (Sphingosine 1-phosphate receptor Edg-1) (S1P receptor Edg-1) (CD antigen CD363)
Gene: S1PR1
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.54 | 1.00 | 0.740 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 8626678 |
| Identification Methods | affinity chromatography technology, pull down, two hybrid |
| Interaction Type | physical association, direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | 7tm_1~G-alpha |
| Common GO terms | GO:0001664 - G protein-coupled receptor binding GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0007193 - adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
