HitPredict

Interactor 1: GNAI3 (P08754)
Guanine nucleotide-binding protein G(i) subunit alpha-3 (G(i) alpha-3)
Gene: GNAI3

Interactor 2: RPGP1 (P47736)
Rap1 GTPase-activating protein 1 (Rap1GAP) (Rap1GAP1)
Gene: RAP1GAP

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	1.00	0.861

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	G-alpha~GoLoco
Common GO terms	GO:0003924 - GTPase activity GO:0005737 - cytoplasm GO:0016020 - membrane
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 354 Hs			1 663
+	Hs
		580407 GNAZ_HUMAN (1-353): 7.65e-156: 443: 67.23		RPGP1_HUMAN (1-663): 0: 837: 100.00
+	Dm
		558491 GNAO_DROME (1-354): 1.51e-161: 457: 69.01		Q9VM00_DROME (33-663): 0: 695: 40.37
+	Ce
		851066 GNAO_CAEEL (1-354): 1.17e-166: 470: 69.86		Q965M4_CAEEL (1-529): 0: 600: 41.31
+	Ce
		851060 GNAO_CAEEL (1-354): 1.17e-166: 470: 69.86		Q86RS9_CAEEL (1-529): 0: 599: 41.31