Interactor 1: SIR2 (P06700)
NAD-dependent histone deacetylase SIR2 (EC 2.3.1.286) (Regulatory protein SIR2) (Silent information regulator 2)
Gene: SIR2
Interactor 2: SIR1 (P21691)
Regulatory protein SIR1 (Heterochromatin protein SIR1) (Silent information regulator 1)
Gene: SIR1
Species: Saccharomyces cerevisiae S288C
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.44 | 0.55 | 0.493 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 17043313 |
| Identification Methods | affinity chromatography technology, tandem affinity purification |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005677 - chromatin silencing complex GO:0030466 - silent mating-type cassette heterochromatin formation GO:0031507 - heterochromatin formation |
| Homologous interactions | 0 |
Service provided by Combinatics, Japan
Last updated: 11Aug2025
