HitPredict

Interactor 1: GNAI3 (P08754)
Guanine nucleotide-binding protein G(i) subunit alpha-3 (G(i) alpha-3)
Gene: GNAI3

Interactor 2: DUS22 (Q9NRW4)
Dual specificity protein phosphatase 22 (EC 3.1.3.16) (EC 3.1.3.48) (JNK-stimulatory phosphatase-1) (JSP-1) (Low molecular weight dual specificity phosphatase 2) (LMW-DSP2) (Mitogen-activated protein kinase phosphatase x) (MAP kinase phosphatase x) (MKP-x)
Gene: DUSP22

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	27432908
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 354 Hs			1 184
+	Hs
		926719 GNAI1_HUMAN (1-354): 4.65e-179: 502: 93.79		DUS22_HUMAN (1-184): 4.7e-77: 229: 100.00
+	Hs
		391472 GNAI2_HUMAN (1-354): 2.82e-174: 489: 85.92		DUS22_HUMAN (1-184): 4.7e-77: 229: 100.00
+	Hs
		451043 GNAO_HUMAN (1-354): 6.89e-171: 481: 71.27		DUS22_HUMAN (1-184): 4.7e-77: 229: 100.00
+	Hs
		444775 GNAI3_HUMAN (1-354): 1.47e-176: 495: 100.00		DUS9_HUMAN (5-170): 2.3e-61: 196: 33.53
+	Hs
		926689 GNAI1_HUMAN (1-354): 4.65e-179: 502: 93.79		DUS6_HUMAN (5-157): 3.76e-58: 188: 35.26
+	Hs
		837651 GNAQ_HUMAN (1-353): 1.65e-161: 457: 51.41		DUS22_HUMAN (1-184): 4.7e-77: 229: 100.00
+	Hs
		391454 GNAI2_HUMAN (1-354): 2.82e-174: 489: 85.92		DUS9_HUMAN (5-170): 2.3e-61: 196: 33.53
+	Hs
		444739 GNAI3_HUMAN (1-354): 1.47e-176: 495: 100.00		DUS6_HUMAN (5-157): 3.76e-58: 188: 35.26
+	Hs
		391386 GNAI2_HUMAN (1-354): 2.82e-174: 489: 85.92		DUS4_HUMAN (4-161): 4.72e-59: 190: 31.45
+	Hs
		325971 GNA14_HUMAN (3-353): 3.49e-158: 448: 50.71		DUS22_HUMAN (1-184): 4.7e-77: 229: 100.00
+	Hs
		391406 GNAI2_HUMAN (1-354): 2.82e-174: 489: 85.92		DUS6_HUMAN (5-157): 3.76e-58: 188: 35.26
+	Hs
		670490 GNA11_HUMAN (1-353): 1.31e-156: 445: 50.28		DUS22_HUMAN (1-184): 4.7e-77: 229: 100.00
+	Hs
		1053443 GNA13_HUMAN (2-353): 2.06e-152: 435: 38.33		DUS22_HUMAN (1-184): 4.7e-77: 229: 100.00
+	Hs
		670484 GNA11_HUMAN (1-353): 1.31e-156: 445: 50.28		DUS9_HUMAN (5-170): 2.3e-61: 196: 33.53
+	Hs
		926593 GNAS2_HUMAN (1-353): 1.44e-139: 403: 38.68		DUS6_HUMAN (5-157): 3.76e-58: 188: 35.26