HitPredict

Interactor 1: K1C16 (P08779)
Keratin, type I cytoskeletal 16 (Cytokeratin-16) (CK-16) (Keratin-16) (K16)
Gene: KRT16

Interactor 2: PPR18 (Q6NYC8)
Phostensin (Protein phosphatase 1 F-actin cytoskeleton-targeting subunit) (Protein phosphatase 1 regulatory subunit 18)
Gene: PPP1R18

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.61	0.60	0.606

Property	Details
Experiments	32296183, unassigned1304
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005856 - cytoskeleton
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 473 Hs			1 613
+	Hs
		580042 K1C15_HUMAN (116-429): 2.97e-155: 450: 76.19		PPR18_HUMAN (1-613): 8.33e-74: 249: 100.00
+	Hs
		444396 K1C19_HUMAN (106-434): 2.34e-146: 425: 69.61		PPR18_HUMAN (1-613): 8.33e-74: 249: 100.00
+	Hs
		1071222 K1H1_HUMAN (67-443): 1.23e-142: 416: 51.72		PPR18_HUMAN (1-613): 8.33e-74: 249: 100.00
+	Hs
		49568 A1A4E9_HUMAN (105-441): 5.96e-141: 413: 69.53		PPR18_HUMAN (1-613): 8.33e-74: 249: 100.00
+	Hs
		531482 K1C13_HUMAN (105-441): 5.96e-141: 413: 69.82		PPR18_HUMAN (1-613): 8.33e-74: 249: 100.00
+	Hs
		1157413 K1C27_HUMAN (104-435): 7.62e-122: 365: 59.94		PPR18_HUMAN (1-613): 8.33e-74: 249: 100.00
+	Hs
		1055056 KT33B_HUMAN (110-430): 7.99e-122: 363: 59.19		PPR18_HUMAN (1-613): 8.33e-74: 249: 100.00
+	Hs
		280613 KRT34_HUMAN (110-437): 1.12e-117: 352: 56.16		PPR18_HUMAN (1-613): 8.33e-74: 249: 100.00
+	Hs
		280807 KRT36_HUMAN (2-428): 1.77e-80: 258: 53.86		PPR18_HUMAN (1-613): 8.33e-74: 249: 100.00