HitPredict

Interactor 1: IL6RA (P08887)
Interleukin-6 receptor subunit alpha (IL-6 receptor subunit alpha) (IL-6R subunit alpha) (IL-6R-alpha) (IL-6RA) (IL-6R 1) (Membrane glycoprotein 80) (gp80) (CD antigen CD126) [Cleaved into: Soluble interleukin-6 receptor subunit alpha (sIL6R)]
Gene: IL6R

Interactor 2: FBX2 (Q9UK22)
F-box only protein 2
Gene: FBXO2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	32549792
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 468 Hs			1 296
+	Hs
		770211 IL6RB_HUMAN (1-364): 1.51e-73: 250: 17.19		FBX2_HUMAN (1-296): 5.13e-147: 416: 100.00
+	Hs
		265802 CRLF1_HUMAN (15-410): 2.93e-63: 212: 19.95		FBX2_HUMAN (1-296): 5.13e-147: 416: 100.00
+	Hs
		1305437 OSMR_HUMAN (28-405): 3.96e-47: 176: 12.56		FBX2_HUMAN (1-296): 5.13e-147: 416: 100.00
+	Hs
		789685 LIFR_HUMAN (27-419): 6.23e-47: 176: 11.69		FBX2_HUMAN (1-296): 5.13e-147: 416: 100.00
+	Hs
		789684 LIFR_HUMAN (27-419): 6.23e-47: 176: 11.69		FBX6_HUMAN (40-296): 2.4e-133: 381: 49.81
+	Hs
		1032042 PTPRS_HUMAN (74-394): 3.26e-26: 114: 10.21		FBX2_HUMAN (1-296): 5.13e-147: 416: 100.00
+	Hs
		685328 L1CAM_HUMAN (58-403): 5.7e-23: 104: 11.38		FBX2_HUMAN (1-296): 5.13e-147: 416: 100.00
+	Hs
		817334 LEPR_HUMAN (118-323): 6.02e-20: 95.4: 16.06		FBX2_HUMAN (1-296): 5.13e-147: 416: 100.00
+	Hs
		1032034 PTPRS_HUMAN (74-394): 3.26e-26: 114: 10.21		FBX6_HUMAN (40-296): 2.4e-133: 381: 49.81
+	Hs
		1018314 CNTN1_HUMAN (13-155): 1.74e-12: 71.9: 15.75		FBX2_HUMAN (1-296): 5.13e-147: 416: 100.00
+	Hs
		685320 L1CAM_HUMAN (58-403): 5.7e-23: 104: 11.38		FBX6_HUMAN (40-296): 2.4e-133: 381: 49.81
+	Hs
		817333 LEPR_HUMAN (118-323): 6.02e-20: 95.4: 16.06		FBX6_HUMAN (40-296): 2.4e-133: 381: 49.81