HitPredict

Interactor 1: ROS1 (P08922)
Proto-oncogene tyrosine-protein kinase ROS (EC 2.7.10.1) (Proto-oncogene c-Ros) (Proto-oncogene c-Ros-1) (Receptor tyrosine kinase c-ros oncogene 1) (c-Ros receptor tyrosine kinase)
Gene: ROS1

Interactor 2: UBE2N (P61088)
Ubiquitin-conjugating enzyme E2 N (EC 2.3.2.23) (Bendless-like ubiquitin-conjugating enzyme) (E2 ubiquitin-conjugating enzyme N) (Ubc13) (UbcH13) (Ubiquitin carrier protein N) (Ubiquitin-protein ligase N)
Gene: UBE2N

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 2347 Hs			1 152
+	Hs
		896558 EPHA6_HUMAN (1385-2290): 1.92e-174: 566: 18.96		UBE2N_HUMAN (1-152): 1.51e-73: 218: 100.00
+	Hs
		435592 IGF1R_HUMAN (1442-2307): 3.63e-161: 538: 23.25		UBE2N_HUMAN (1-152): 1.51e-73: 218: 100.00
+	Hs
		896419 TIE2_HUMAN (1622-2244): 6.15e-134: 453: 26.28		UBE2N_HUMAN (1-152): 1.51e-73: 218: 100.00
+	Hs
		674377 UFO_HUMAN (1633-2297): 6.04e-130: 434: 25.83		UBE2N_HUMAN (1-152): 1.51e-73: 218: 100.00
+	Hs
		896566 ALK_HUMAN (1858-2311): 4.31e-84: 309: 38.96		UBE2N_HUMAN (1-152): 1.51e-73: 218: 100.00
+	Hs
		666567 LTK_HUMAN (1945-2244): 3.23e-82: 293: 45.93		UB2D3_HUMAN (4-149): 1.46e-78: 230: 45.89
+	Hs
		666568 LTK_HUMAN (1945-2244): 3.23e-82: 293: 45.93		UBE2N_HUMAN (1-152): 1.51e-73: 218: 100.00
+	Hs
		609235 FGFR3_HUMAN (1886-2215): 4.22e-59: 222: 38.73		UBE2N_HUMAN (1-152): 1.51e-73: 218: 100.00
+	Hs
		609211 FGFR3_HUMAN (1886-2215): 4.22e-59: 222: 38.73		UBE2A_HUMAN (1-146): 5.35e-70: 209: 39.46