Interactor 1: TOLL (P08953)
Protein toll
Gene: Tl
Interactor 2: SPZ (P48607)
Protein spaetzle [Cleaved into: Protein spaetzle C-106]
Gene: SPZ
Species: Drosophila melanogaster
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.95 | 1.00 | 0.977 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 12872120, 15795223, 23729564, 24282309, 15197269, 31088910, 18347020, 20378549, 24733933, unassigned4 |
| Identification Methods | affinity chromatography technology, pull down, x-ray crystallography, coimmunoprecipitation, experimental interaction detection |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | LRR_5~Spaetzle, LRR_8~Spaetzle |
| Common GO terms | GO:0002225 - positive regulation of antimicrobial peptide production GO:0002347 - response to tumor cell GO:0002804 - positive regulation of antifungal peptide production GO:0007526 - larval somatic muscle development GO:0008063 - Toll signaling pathway and 6 others more... |
| Homologous interactions | 7 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
