HitPredict

Interactor 1: TOLL (P08953)
Protein toll
Gene: Tl

Interactor 2: Q58S70 (Q58S70)
Tehao
Gene: Tehao

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.24	1.00	0.492

Property	Details
Experiments	unassigned4
Identification Methods	experimental interaction detection
Interaction Type	physical association

Property	Details
Interacting Pfam domains	TIR_2~TIR_2
Common GO terms	GO:0004888 - transmembrane signaling receptor activity GO:0008063 - Toll signaling pathway GO:0038023 - signaling receptor activity GO:0045087 - innate immune response
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 1097 Dm			1 344
+	Dm
		445971 TOLL_DROME (1-1097): 0: 633: 100.00		Q9VJX9_DROME (25-215): 1.87e-10: 63.9: 15.10
+	Dm
		445962 TOLL_DROME (1-1097): 0: 633: 100.00		TOLL_DROME (26-162): 3.02e-09: 60.5: 15.11
+	Hs
		1316133 TLR9_HUMAN (28-1004): 9.23e-108: 363: 16.78		LRRC3_HUMAN (18-164): 1.06e-15: 77.5: 26.85
+	Hs
		1344372 TLR9_HUMAN (28-1004): 9.23e-108: 363: 16.78		TLR9_HUMAN (4-270): 4.1e-12: 69.3: 14.72
+	Hs
		1344373 TLR9_HUMAN (28-1004): 9.23e-108: 363: 16.78		TLR8_HUMAN (37-165): 6.14e-09: 59.7: 16.78
+	At
		85349 BAME1_ARATH (6-567): 7.5e-90: 312: 15.08		ERL1_ARATH (28-269): 1.17e-20: 95.1: 10.28
+	At
		84594 RGI3_ARATH (4-561): 1.38e-85: 302: 14.79		ERL2_ARATH (28-269): 2.34e-23: 103: 11.81
+	Hs
		1344388 TLR8_HUMAN (26-1006): 4.42e-98: 336: 16.65		TLR7_HUMAN (29-221): 4.27e-10: 63.2: 13.78
+	Hs
		1344387 TLR8_HUMAN (26-1006): 4.42e-98: 336: 16.65		TLR8_HUMAN (37-165): 6.14e-09: 59.7: 16.78
+	Mm
		1322305 TLR9_MOUSE (53-1004): 9.14e-98: 335: 14.98		TLR9_MOUSE (28-138): 8.64e-09: 58.9: 15.45
+	At
		84590 RGI3_ARATH (4-561): 1.38e-85: 302: 14.79		RLK5_ARATH (25-218): 5.43e-18: 87: 11.11
+	At
		812864 EMS1_ARATH (3-499): 4.67e-72: 263: 15.00		RLK5_ARATH (25-218): 5.43e-18: 87: 11.11
+	Hs
		120116 TLR5_HUMAN (63-509): 4.41e-40: 162: 14.79		TLR4_HUMAN (29-340): 1.88e-47: 173: 24.61
+	At
		1325521 PEPR2_ARATH (9-391): 1.41e-50: 196: 14.29		PXC2_ARATH (26-257): 2.37e-18: 88.2: 11.41
+	At
		1108134 TDR_ARATH (8-400): 2.05e-50: 196: 14.43		PRK6_ARATH (65-197): 2.99e-14: 75.5: 12.78
+	At
		1108136 PEPR2_ARATH (9-391): 1.41e-50: 196: 14.29		PRK6_ARATH (65-197): 2.99e-14: 75.5: 12.78
+	Hs
		1166667 LRIG3_HUMAN (262-769): 1.73e-44: 177: 17.81		LRC4C_HUMAN (17-217): 3.94e-11: 66.2: 12.87
+	Mm
		1163943 TLR5_MOUSE (97-509): 1.11e-39: 161: 18.12		TLR11_MOUSE (31-143): 1.98e-14: 76.2: 23.93
+	Hs
		237420 TLR5_HUMAN (63-509): 4.41e-40: 162: 14.79		TLR5_HUMAN (28-148): 1.72e-12: 70.5: 19.20