HitPredict

Interactor 1: CD63 (P08962)
CD63 antigen (Granulophysin) (Lysosomal-associated membrane protein 3) (LAMP-3) (Lysosome integral membrane protein 1) (Limp1) (Melanoma-associated antigen ME491) (OMA81H) (Ocular melanoma-associated antigen) (Tetraspanin-30) (Tspan-30) (CD antigen CD63)
Gene: CD63

Interactor 2: LEG3 (P17931)
Galectin-3 (Gal-3) (35 kDa lectin) (Carbohydrate-binding protein 35) (CBP 35) (Galactose-specific lectin 3) (Galactoside-binding protein) (GALBP) (IgE-binding protein) (L-31) (Laminin-binding protein) (Lectin L-29) (Mac-2 antigen)
Gene: LGALS3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005615 - extracellular space GO:0005654 - nucleoplasm GO:0005886 - plasma membrane GO:0009986 - cell surface GO:0070062 - extracellular exosome
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 238 Hs			1 250
+	Hs
		237783 TSN3_HUMAN (4-236): 4.09e-48: 160: 29.17		LEG3_HUMAN (1-250): 3.29e-96: 283: 100.00
+	Hs
		119104 CD63_HUMAN (1-238): 2.68e-68: 211: 100.00		LEG9_HUMAN (108-249): 3.89e-40: 143: 37.67
+	Hs
		121086 CD63_HUMAN (1-238): 2.68e-68: 211: 100.00		LEG8_HUMAN (105-245): 4.74e-39: 139: 36.11
+	Hs
		446031 CD63_HUMAN (1-238): 2.68e-68: 211: 100.00		LEG9C_HUMAN (108-249): 6.7e-38: 137: 37.67
+	Hs
		449222 CD151_HUMAN (3-232): 2.85e-60: 191: 28.22		LEG1_HUMAN (125-247): 3.18e-43: 144: 28.00
+	Hs
		449188 CD9_HUMAN (1-238): 1.72e-54: 176: 24.49		LEG1_HUMAN (125-247): 3.18e-43: 144: 28.00
+	Hs
		119036 TSN3_HUMAN (4-236): 4.09e-48: 160: 29.17		LEG9_HUMAN (108-249): 3.89e-40: 143: 37.67
+	Hs
		237811 TSN3_HUMAN (4-236): 4.09e-48: 160: 29.17		LEG9C_HUMAN (108-249): 6.7e-38: 137: 37.67