HitPredict

Interactor 1: CD63 (P08962)
CD63 antigen (Granulophysin) (Lysosomal-associated membrane protein 3) (LAMP-3) (Lysosome integral membrane protein 1) (Limp1) (Melanoma-associated antigen ME491) (OMA81H) (Ocular melanoma-associated antigen) (Tetraspanin-30) (Tspan-30) (CD antigen CD63)
Gene: CD63

Interactor 2: PAR2 (P55085)
Proteinase-activated receptor 2 (PAR-2) (Coagulation factor II receptor-like 1) (G-protein coupled receptor 11) (Thrombin receptor-like 1) [Cleaved into: Proteinase-activated receptor 2, alternate cleaved 1; Proteinase-activated receptor 2, alternate cleaved 2]
Gene: F2RL1

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.60	0.541

Property	Details
Experiments	28298427
Identification Methods	two hybrid, ubiquitin reconstruction
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 238 Hs			1 397
+	Hs
		783911 TSN7_HUMAN (1-238): 2.05e-68: 212: 29.92		CCR9_HUMAN (72-396): 3.58e-80: 252: 24.48
+	Hs
		428955 TSN7_HUMAN (1-238): 2.05e-68: 212: 29.92		ADRB2_HUMAN (42-383): 5.38e-71: 230: 14.79
+	Hs
		876180 TSN17_HUMAN (8-235): 4.87e-62: 197: 27.67		PAR2_HUMAN (1-374): 1.43e-74: 239: 100.00
+	Hs
		783809 TSN7_HUMAN (1-238): 2.05e-68: 212: 29.92		CCR2_HUMAN (47-362): 4.05e-68: 221: 24.38
+	Hs
		849732 CD81_HUMAN (1-234): 5.88e-53: 172: 21.63		CCR9_HUMAN (72-396): 3.58e-80: 252: 24.48
+	Hs
		876102 CD81_HUMAN (1-234): 5.88e-53: 172: 21.63		PAR2_HUMAN (1-374): 1.43e-74: 239: 100.00
+	Hs
		237794 TSN3_HUMAN (4-236): 4.09e-48: 160: 29.17		CCR6_HUMAN (72-394): 3.15e-79: 250: 23.57
+	Hs
		326045 TSN15_HUMAN (10-232): 1.41e-47: 160: 23.97		CCR6_HUMAN (72-394): 3.15e-79: 250: 23.57
+	Hs
		237805 TSN3_HUMAN (4-236): 4.09e-48: 160: 29.17		GPR17_HUMAN (57-367): 8.1e-79: 249: 29.02
+	Hs
		326064 TSN15_HUMAN (10-232): 1.41e-47: 160: 23.97		GPR17_HUMAN (57-367): 8.1e-79: 249: 29.02
+	Hs
		428918 CD9_HUMAN (1-238): 1.72e-54: 176: 24.49		ADRB2_HUMAN (42-383): 5.38e-71: 230: 14.79
+	Hs
		428997 CD81_HUMAN (1-234): 5.88e-53: 172: 21.63		ADRB2_HUMAN (42-383): 5.38e-71: 230: 14.79
+	Hs
		237799 TSN3_HUMAN (4-236): 4.09e-48: 160: 29.17		PAR2_HUMAN (1-374): 1.43e-74: 239: 100.00
+	Hs
		208446 TSN15_HUMAN (10-232): 1.41e-47: 160: 23.97		OX2R_HUMAN (23-392): 8.34e-73: 236: 18.93
+	Hs
		326031 TSN15_HUMAN (10-232): 1.41e-47: 160: 23.97		NK3R_HUMAN (32-395): 2.45e-72: 235: 17.60
+	Hs
		722930 CD81_HUMAN (1-234): 5.88e-53: 172: 21.63		ADA1A_HUMAN (54-384): 8.6e-67: 221: 15.92
+	Hs
		783813 CD81_HUMAN (1-234): 5.88e-53: 172: 21.63		CCR2_HUMAN (47-362): 4.05e-68: 221: 24.38
+	Hs
		326034 TSN15_HUMAN (10-232): 1.41e-47: 160: 23.97		AGTR1_HUMAN (48-391): 4.06e-71: 228: 24.29
+	Hs
		237791 TSN3_HUMAN (4-236): 4.09e-48: 160: 29.17		OPRX_HUMAN (40-376): 2.58e-68: 222: 23.75
+	Hs
		326039 TSN15_HUMAN (10-232): 1.41e-47: 160: 23.97		LPAR6_HUMAN (81-356): 6.81e-35: 133: 30.28