HitPredict

Interactor 1: CD63 (P08962)
CD63 antigen (Granulophysin) (Lysosomal-associated membrane protein 3) (LAMP-3) (Lysosome integral membrane protein 1) (Limp1) (Melanoma-associated antigen ME491) (OMA81H) (Ocular melanoma-associated antigen) (Tetraspanin-30) (Tspan-30) (CD antigen CD63)
Gene: CD63

Interactor 2: TSC1 (Q92574)
Hamartin (Tuberous sclerosis 1 protein)
Gene: TSC1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.60	0.457

Property	Details
Experiments	17355907
Identification Methods	two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005765 - lysosomal membrane GO:0005886 - plasma membrane GO:0007160 - cell-matrix adhesion
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 238 Hs			1 1164
+	Hs
		522557 TSN33_HUMAN (10-234): 6.51e-59: 189: 29.96		MYH1_HUMAN (393-967): 5.76e-21: 102: 11.23
+	Hs
		1199573 TSN33_HUMAN (10-234): 6.51e-59: 189: 29.96		MYH2_HUMAN (393-980): 6.89e-21: 101: 11.32
+	Hs
		1199577 TSN33_HUMAN (10-234): 6.51e-59: 189: 29.96		MYH4_HUMAN (393-969): 2.58e-19: 96.8: 11.22
+	Hs
		724736 CD81_HUMAN (1-234): 5.88e-53: 172: 21.63		MYH9_HUMAN (673-1164): 1.25e-23: 111: 12.40
+	Hs
		522625 TSN33_HUMAN (10-234): 6.51e-59: 189: 29.96		MYH7_HUMAN (391-922): 3.39e-17: 89.9: 8.59
+	Hs
		551648 CD81_HUMAN (1-234): 5.88e-53: 172: 21.63		DESP_HUMAN (570-1151): 1.05e-21: 104: 11.54
+	Hs
		528414 TSN33_HUMAN (10-234): 6.51e-59: 189: 29.96		MYH8_HUMAN (822-1163): 6.53e-11: 69.1: 10.73
+	Hs
		1199574 TSN33_HUMAN (10-234): 6.51e-59: 189: 29.96		MYH13_HUMAN (628-994): 2.22e-10: 67.5: 20.45