HitPredict

Interactor 1: SNRPA (P09012)
U1 small nuclear ribonucleoprotein A (U1 snRNP A) (U1-A) (U1A)
Gene: SNRPA

Interactor 2: TIA1 (P31483)
Cytotoxic granule associated RNA binding protein TIA1 (Nucleolysin TIA-1 isoform p40) (RNA-binding protein TIA-1) (T-cell-restricted intracellular antigen-1) (TIA-1) (p40-TIA-1)
Gene: TIA1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.44	1.00	0.665

Property	Details
Experiments	12486009
Identification Methods	anti bait coimmunoprecipitation, pull down
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 282 Hs			1 386
+	Hs
		320990 PTBP3_HUMAN (2-281): 3.29e-49: 172: 19.44		TIA1_HUMAN (1-386): 3.24e-111: 332: 100.00
+	Hs
		446592 SNRPA_HUMAN (1-282): 4.82e-60: 193: 100.00		TIAR_HUMAN (1-386): 5.19e-88: 272: 73.01
+	Mm
		665745 PABP1_MOUSE (10-219): 2.94e-20: 92.2: 15.09		TIA1_MOUSE (1-386): 1.13e-110: 330: 96.63
+	Hs
		47766 RBM47_HUMAN (12-281): 2.3e-39: 146: 18.68		TIAR_HUMAN (1-386): 5.19e-88: 272: 73.01
+	Hs
		516471 PABP1_HUMAN (10-219): 3.06e-20: 92.2: 15.09		TIAR_HUMAN (1-386): 5.19e-88: 272: 73.01
+	Hs
		321161 PTBP3_HUMAN (2-281): 3.29e-49: 172: 19.44		PABP5_HUMAN (2-187): 2.52e-44: 159: 22.63
+	Hs
		47742 RBM47_HUMAN (12-281): 2.3e-39: 146: 18.68		PABP1_HUMAN (96-297): 6.74e-33: 131: 26.70
+	Sc
		693953 PUB1_YEAST (11-282): 2.91e-39: 144: 18.25		PUB1_YEAST (7-185): 4.38e-31: 124: 40.56
+	Sc
		376696 RU1A_YEAST (1-281): 3.81e-48: 163: 20.42		PABP_YEAST (1-104): 6.86e-19: 90.1: 19.05
+	Hs
		516635 PABP1_HUMAN (10-219): 3.06e-20: 92.2: 15.09		PABP5_HUMAN (2-187): 2.52e-44: 159: 22.63
+	Hs
		1119141 PAP1L_HUMAN (11-220): 7.86e-18: 84.9: 18.96		PABP5_HUMAN (2-187): 2.52e-44: 159: 22.63
+	Hs
		47770 RBM47_HUMAN (12-281): 2.3e-39: 146: 18.68		PABP4_HUMAN (1-98): 1.32e-20: 95.5: 21.43
+	Sc
		376694 PUB1_YEAST (11-282): 2.91e-39: 144: 18.25		PABP_YEAST (1-104): 6.86e-19: 90.1: 19.05
+	Hs
		516339 PABP1_HUMAN (10-219): 3.06e-20: 92.2: 15.09		PABP1_HUMAN (96-297): 6.74e-33: 131: 26.70
+	Hs
		474021 PABP4_HUMAN (11-199): 1.25e-18: 87.6: 18.42		PAB4L_HUMAN (104-299): 1.73e-34: 132: 24.00
+	Hs
		516689 PABP1_HUMAN (10-219): 3.06e-20: 92.2: 15.09		PABP3_HUMAN (96-297): 5.07e-30: 123: 25.73
+	Hs
		516495 PABP1_HUMAN (10-219): 3.06e-20: 92.2: 15.09		PABP4_HUMAN (1-98): 1.32e-20: 95.5: 21.43
+	Sc
		376562 PABP_YEAST (3-199): 1.47e-17: 84.2: 10.05		PABP_YEAST (1-104): 6.86e-19: 90.1: 19.05
+	Zm
		8143 A0A1D6ELH4_MAIZE (8-215): 7.46e-19: 88: 19.91		A0A1D6ELH4_MAIZE (217-294): 7e-09: 59.7: 22.62