HitPredict

Interactor 1: SNRPA (P09012)
U1 small nuclear ribonucleoprotein A (U1 snRNP A) (U1-A) (U1A)
Gene: SNRPA

Interactor 2: CIRBP (Q14011)
Cold-inducible RNA-binding protein (A18 hnRNP) (Glycine-rich RNA-binding protein CIRP)
Gene: CIRBP

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.811

Property	Details
Experiments	25416956, 31515488
Identification Methods	two hybrid, validated two hybrid, two hybrid prey pooling approach, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005681 - spliceosomal complex
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 282 Hs			1 172
+	Hs
		446589 SNRPA_HUMAN (1-282): 4.82e-60: 193: 100.00		RBM3_HUMAN (1-166): 4.5e-33: 116: 54.22
+	Hs
		483438 RBY1A_HUMAN (1-280): 3.76e-46: 163: 17.48		CIRBP_HUMAN (1-172): 1.12e-39: 134: 100.00
+	Hs
		483437 RBY1A_HUMAN (1-280): 3.76e-46: 163: 17.48		RBM3_HUMAN (1-166): 4.5e-33: 116: 54.22
+	Hs
		446529 SNRPA_HUMAN (1-282): 4.82e-60: 193: 100.00		RBMX_HUMAN (2-86): 3.45e-18: 82: 62.35
+	Hs
		446516 SNRPA_HUMAN (1-282): 4.82e-60: 193: 100.00		TIA1_HUMAN (2-164): 7.27e-18: 81.1: 17.78
+	Hs
		446592 SNRPA_HUMAN (1-282): 4.82e-60: 193: 100.00		TIAR_HUMAN (2-151): 1.75e-16: 77.2: 20.53
+	Hs
		446491 SNRPA_HUMAN (1-282): 4.82e-60: 193: 100.00		RBY1A_HUMAN (2-118): 7.64e-16: 75.9: 51.28
+	Hs
		446576 SNRPA_HUMAN (1-282): 4.82e-60: 193: 100.00		TRA2B_HUMAN (8-132): 2.95e-15: 73.2: 46.40
+	Hs
		446646 SNRPA_HUMAN (1-282): 4.82e-60: 193: 100.00		RBY1F_HUMAN (2-118): 1.22e-14: 72.4: 49.57
+	Hs
		446545 SNRPA_HUMAN (1-282): 4.82e-60: 193: 100.00		ROA3_HUMAN (7-92): 2.98e-14: 70.9: 43.02
+	Hs
		321162 PTBP3_HUMAN (2-281): 3.29e-49: 172: 19.44		RMXL1_HUMAN (2-86): 1.01e-18: 83.6: 62.35
+	Hs
		320990 PTBP3_HUMAN (2-281): 3.29e-49: 172: 19.44		TIA1_HUMAN (2-164): 7.27e-18: 81.1: 17.78
+	Hs
		62458 RBY1E_HUMAN (1-280): 1.76e-46: 164: 17.48		RBMX_HUMAN (2-86): 3.45e-18: 82: 62.35
+	Hs
		483431 RBY1A_HUMAN (1-280): 3.76e-46: 163: 17.48		RBMX_HUMAN (2-86): 3.45e-18: 82: 62.35
+	Hs
		745179 RBY1F_HUMAN (1-280): 7.88e-46: 162: 17.48		RBMX_HUMAN (2-86): 3.45e-18: 82: 62.35
+	Hs
		483430 RBY1A_HUMAN (1-280): 3.76e-46: 163: 17.48		RBY1A_HUMAN (2-118): 7.64e-16: 75.9: 51.28
+	Hs
		62459 RBY1E_HUMAN (1-280): 1.76e-46: 164: 17.48		RBY1F_HUMAN (2-118): 1.22e-14: 72.4: 49.57
+	Hs
		483440 RBY1A_HUMAN (1-280): 3.76e-46: 163: 17.48		RBY1F_HUMAN (2-118): 1.22e-14: 72.4: 49.57