HitPredict

Interactor 1: SNRPA (P09012)
U1 small nuclear ribonucleoprotein A (U1 snRNP A) (U1-A) (U1A)
Gene: SNRPA

Interactor 2: U5S1 (Q15029)
116 kDa U5 small nuclear ribonucleoprotein component (Elongation factor Tu GTP-binding domain-containing protein 2) (SNU114 homolog) (hSNU114) (U5 snRNP-specific protein, 116 kDa) (U5-116 kDa)
Gene: EFTUD2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0046540 - U4/U6 x U5 tri-snRNP complex
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 282 Hs			1 972
+	Hs
		441289 RU2B_HUMAN (5-282): 1.37e-59: 190: 46.40		U5S1_HUMAN (1-972): 0: 1062: 100.00
+	Hs
		643511 PTBP1_HUMAN (1-281): 2.58e-55: 189: 20.42		U5S1_HUMAN (1-972): 0: 1062: 100.00
+	Hs
		516526 PABP1_HUMAN (10-219): 3.06e-20: 92.2: 15.09		U5S1_HUMAN (1-972): 0: 1062: 100.00
+	Hs
		1031337 PABP4_HUMAN (11-199): 1.25e-18: 87.6: 18.42		U5S1_HUMAN (1-972): 0: 1062: 100.00
+	Sp
		292955 RU2B_SCHPO (10-117): 1.85e-40: 137: 38.89		SN114_SCHPO (1-970): 0: 928: 54.22
+	Sp
		292934 PABP_SCHPO (10-199): 3.45e-19: 89.2: 13.02		SN114_SCHPO (1-970): 0: 928: 54.22
+	Sc
		696630 RU1A_YEAST (1-281): 3.81e-48: 163: 20.42		SN114_YEAST (3-967): 0: 692: 32.82
+	Sc
		693990 PUB1_YEAST (11-282): 2.91e-39: 144: 18.25		SN114_YEAST (3-967): 0: 692: 32.82
+	Sc
		731732 MSL1_YEAST (1-94): 7.06e-31: 113: 31.92		SN114_YEAST (3-967): 0: 692: 32.82