HitPredict

Interactor 1: SNRPA (P09012)
U1 small nuclear ribonucleoprotein A (U1 snRNP A) (U1-A) (U1A)
Gene: SNRPA

Interactor 2: LARP7 (Q4G0J3)
La-related protein 7 (La ribonucleoprotein domain family member 7) (hLARP7) (P-TEFb-interaction protein for 7SK stability) (PIP7S)
Gene: LARP7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	1.00	0.789

Property	Details
Experiments	29845934, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	La~RRM_1, RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 282 Hs			1 582
+	Hs
		441303 RU2B_HUMAN (5-282): 1.37e-59: 190: 46.40		LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00
+	Sc
		696628 RU1A_YEAST (1-281): 3.81e-48: 163: 20.42		LHP1_YEAST (7-270): 1.34e-45: 163: 22.74
+	Sc
		693977 PUB1_YEAST (11-282): 2.91e-39: 144: 18.25		LHP1_YEAST (7-270): 1.34e-45: 163: 22.74
+	Hs
		47770 RBM47_HUMAN (12-281): 2.3e-39: 146: 18.68		PABP4_HUMAN (1-208): 8.15e-41: 158: 11.98
+	Hs
		47742 RBM47_HUMAN (12-281): 2.3e-39: 146: 18.68		PABP1_HUMAN (1-405): 1.94e-40: 157: 10.29
+	Hs
		47799 RBM47_HUMAN (12-281): 2.3e-39: 146: 18.68		LARP4_HUMAN (22-216): 3.23e-40: 157: 21.32
+	Hs
		321161 PTBP3_HUMAN (2-281): 3.29e-49: 172: 19.44		PABP5_HUMAN (12-206): 7.64e-32: 128: 14.15
+	Sc
		376696 RU1A_YEAST (1-281): 3.81e-48: 163: 20.42		PABP_YEAST (9-243): 8.44e-33: 134: 13.47
+	Hs
		47827 RBM47_HUMAN (12-281): 2.3e-39: 146: 18.68		LAR4B_HUMAN (2-216): 8.48e-36: 145: 17.02
+	At
		285478 PABP8_ARATH (2-248): 1.13e-20: 93.4: 15.63		LRP6B_ARATH (2-265): 6.42e-54: 194: 21.20
+	Hs
		321221 PTBP3_HUMAN (2-281): 3.29e-49: 172: 19.44		RBM28_HUMAN (40-343): 2.97e-23: 106: 13.84
+	Sc
		376694 PUB1_YEAST (11-282): 2.91e-39: 144: 18.25		PABP_YEAST (9-243): 8.44e-33: 134: 13.47
+	Hs
		446653 SNRPA_HUMAN (1-282): 4.82e-60: 193: 100.00		ELAV1_HUMAN (92-211): 7.72e-13: 71.9: 22.50
+	Hs
		643518 PTBP1_HUMAN (1-281): 2.58e-55: 189: 20.42		ELAV1_HUMAN (92-211): 7.72e-13: 71.9: 22.50
+	Hs
		516339 PABP1_HUMAN (10-219): 3.06e-20: 92.2: 15.09		PABP1_HUMAN (1-405): 1.94e-40: 157: 10.29
+	Hs
		321088 PTBP3_HUMAN (2-281): 3.29e-49: 172: 19.44		ELAV1_HUMAN (92-211): 7.72e-13: 71.9: 22.50
+	Dm
		582593 SNRPA_DROME (197-282): 5.87e-36: 129: 75.58		SXL_DROME (59-259): 1.13e-24: 107: 20.29
+	Hs
		47798 RBM47_HUMAN (12-281): 2.3e-39: 146: 18.68		LARP1_HUMAN (29-114): 6.35e-13: 73.8: 40.23
+	Hs
		47781 RBM47_HUMAN (12-281): 2.3e-39: 146: 18.68		ELAV1_HUMAN (92-211): 7.72e-13: 71.9: 22.50
+	Mm
		665745 PABP1_MOUSE (10-219): 2.94e-20: 92.2: 15.09		TIA1_MOUSE (120-325): 5.06e-24: 106: 13.94