HitPredict

Interactor 1: NPM (P06748)
Nucleophosmin (NPM) (Nucleolar phosphoprotein B23) (Nucleolar protein NO38) (Numatrin)
Gene: NPM1

Interactor 2: SMCA4 (P51532)
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4 (SMARCA4) (EC 3.6.4.-) (BRG1-associated factor 190A) (BAF190A) (Mitotic growth and transcription activator) (Protein BRG-1) (Protein brahma homolog 1) (SNF2-beta) (Transcription activator BRG1)
Gene: SMARCA4

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

The method score is based on:

Property	Details
Experiments	39501047, 20460684
Identification Methods	cross-linking study, affinity chromatography technology
Interaction Type	physical association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003682 - chromatin binding GO:0003713 - transcription coactivator activity GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm and 9 others more... GO:0005730 - nucleolus GO:0006338 - chromatin remodeling GO:0008284 - positive regulation of cell population proliferation GO:0016020 - membrane GO:0030957 - Tat protein binding GO:0032991 - protein-containing complex GO:0042393 - histone binding GO:0045893 - positive regulation of DNA-templated transcription GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1	294
Hs

1	1647

Service provided by Combinatics, Japan

Last updated: 11Aug2025