HitPredict

Interactor 1: SNRPA (P09012)
U1 small nuclear ribonucleoprotein A (U1 snRNP A) (U1-A) (U1A)
Gene: SNRPA

Interactor 2: SYF1 (Q9HCS7)
Pre-mRNA-splicing factor SYF1 (Protein HCNP) (XPA-binding protein 2)
Gene: XAB2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 282 Hs			1 855
+	Hs
		441376 RU2B_HUMAN (5-282): 1.37e-59: 190: 46.40		SYF1_HUMAN (1-855): 0: 602: 100.00
+	Sc
		775724 MSL1_YEAST (1-94): 7.06e-31: 113: 31.92		SYF1_YEAST (19-733): 1.86e-87: 298: 22.31
+	Hs
		446782 SNRPA_HUMAN (1-282): 4.82e-60: 193: 100.00		CRNL1_HUMAN (166-822): 5.62e-47: 182: 14.51
+	Hs
		441365 RU2B_HUMAN (5-282): 1.37e-59: 190: 46.40		CRNL1_HUMAN (166-822): 5.62e-47: 182: 14.51
+	Hs
		446677 SNRPA_HUMAN (1-282): 4.82e-60: 193: 100.00		CTR9_HUMAN (44-847): 4.01e-41: 165: 10.93
+	Hs
		174565 SNRPA_HUMAN (1-282): 4.82e-60: 193: 100.00		OGT1_HUMAN (7-468): 1.59e-37: 154: 13.55
+	Hs
		174637 PTBP1_HUMAN (1-281): 2.58e-55: 189: 20.42		OGT1_HUMAN (7-468): 1.59e-37: 154: 13.55
+	Hs
		446637 SNRPA_HUMAN (1-282): 4.82e-60: 193: 100.00		SART3_HUMAN (18-578): 1.7e-31: 134: 12.80
+	Hs
		174517 PTBP3_HUMAN (2-281): 3.29e-49: 172: 19.44		OGT1_HUMAN (7-468): 1.59e-37: 154: 13.55
+	Hs
		441287 RU2B_HUMAN (5-282): 1.37e-59: 190: 46.40		SART3_HUMAN (18-578): 1.7e-31: 134: 12.80
+	Hs
		300036 SNRPA_HUMAN (1-282): 4.82e-60: 193: 100.00		PRP6_HUMAN (2-353): 4.69e-26: 117: 12.92
+	Hs
		300033 RU2B_HUMAN (5-282): 1.37e-59: 190: 46.40		PRP6_HUMAN (2-353): 4.69e-26: 117: 12.92
+	Mm
		665754 PABP1_MOUSE (10-219): 2.94e-20: 92.2: 15.09		CTR9_MOUSE (44-847): 2.92e-40: 162: 11.34
+	Hs
		1020325 ELAV2_HUMAN (156-281): 1.34e-13: 71.8: 15.91		CRNL1_HUMAN (166-822): 5.62e-47: 182: 14.51
+	Hs
		174583 PABP1_HUMAN (10-219): 3.06e-20: 92.2: 15.09		OGT1_HUMAN (7-468): 1.59e-37: 154: 13.55
+	Hs
		174849 PABP4_HUMAN (11-199): 1.25e-18: 87.6: 18.42		OGT1_HUMAN (7-468): 1.59e-37: 154: 13.55
+	Sp
		1015540 RU2B_SCHPO (10-117): 1.85e-40: 137: 38.89		PRP1_SCHPO (3-435): 4.99e-19: 94.7: 13.66
+	Sc
		694242 PUB1_YEAST (11-282): 2.91e-39: 144: 18.25		RRP5_YEAST (507-723): 1.31e-11: 70.9: 15.46
+	Sc
		775731 MSL1_YEAST (1-94): 7.06e-31: 113: 31.92		CLF1_YEAST (3-250): 5.35e-11: 68.5: 12.06
+	Sc
		376930 PABP_YEAST (3-199): 1.47e-17: 84.2: 10.05		RRP5_YEAST (507-723): 1.31e-11: 70.9: 15.46