HitPredict

Interactor 1: SNRPA (P09012)
U1 small nuclear ribonucleoprotein A (U1 snRNP A) (U1-A) (U1A)
Gene: SNRPA

Interactor 2: SRPK3 (Q9UPE1)
SRSF protein kinase 3 (EC 2.7.11.1) (Muscle-specific serine kinase 1) (MSSK-1) (Serine/arginine-rich protein-specific kinase 3) (SR-protein-specific kinase 3) (Serine/threonine-protein kinase 23)
Gene: SRPK3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.811

Property	Details
Experiments	32707033, 23602568
Identification Methods	affinity chromatography technology, pull down, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Pkinase~RRM_1
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 282 Hs			1 567
+	Hs
		446509 SNRPA_HUMAN (1-282): 4.82e-60: 193: 100.00		CDK2_HUMAN (274-566): 4.84e-82: 260: 17.97
+	Hs
		625126 PTBP1_HUMAN (1-281): 2.58e-55: 189: 20.42		CDK2_HUMAN (274-566): 4.84e-82: 260: 17.97
+	Hs
		446581 SNRPA_HUMAN (1-282): 4.82e-60: 193: 100.00		SRPK2_HUMAN (297-566): 8.12e-72: 244: 57.69
+	Hs
		643476 PTBP1_HUMAN (1-281): 2.58e-55: 189: 20.42		SRPK2_HUMAN (297-566): 8.12e-72: 244: 57.69
+	Hs
		320978 PTBP3_HUMAN (2-281): 3.29e-49: 172: 19.44		CDK2_HUMAN (274-566): 4.84e-82: 260: 17.97
+	Hs
		643453 PTBP1_HUMAN (1-281): 2.58e-55: 189: 20.42		GSK3B_HUMAN (23-336): 1.58e-67: 226: 16.87
+	Hs
		213884 RU2B_HUMAN (5-282): 1.37e-59: 190: 46.40		DYRK3_HUMAN (30-220): 7.68e-65: 223: 29.84
+	Hs
		446542 SNRPA_HUMAN (1-282): 4.82e-60: 193: 100.00		CLK2_HUMAN (60-227): 1.39e-63: 218: 32.54
+	Hs
		446756 SNRPA_HUMAN (1-282): 4.82e-60: 193: 100.00		SRPK1_HUMAN (368-566): 2.74e-59: 210: 67.84
+	Hs
		321020 PTBP3_HUMAN (2-281): 3.29e-49: 172: 19.44		GSK3B_HUMAN (23-336): 1.58e-67: 226: 16.87
+	Sc
		694216 PUB1_YEAST (11-282): 2.91e-39: 144: 18.25		SKY1_YEAST (10-266): 1.03e-71: 245: 40.23
+	Hs
		47828 RBM47_HUMAN (12-281): 2.3e-39: 146: 18.68		DYRK2_HUMAN (344-565): 4.02e-65: 224: 25.82
+	Hs
		446657 SNRPA_HUMAN (1-282): 4.82e-60: 193: 100.00		MK14_HUMAN (66-259): 1.61e-45: 165: 21.78
+	Hs
		516362 PABP1_HUMAN (10-219): 3.06e-20: 92.2: 15.09		CDK2_HUMAN (274-566): 4.84e-82: 260: 17.97
+	Hs
		516416 PABP1_HUMAN (10-219): 3.06e-20: 92.2: 15.09		CLK2_HUMAN (60-227): 1.39e-63: 218: 32.54
+	Rn
		600488 PABP1_RAT (10-219): 3.21e-20: 92.2: 15.09		MK03_RAT (75-267): 1.43e-44: 164: 20.90
+	Hs
		321019 PTBP3_HUMAN (2-281): 3.29e-49: 172: 19.44		CLK3_HUMAN (396-565): 4.23e-12: 70.9: 25.97
+	Hs
		483432 RBY1A_HUMAN (1-280): 3.76e-46: 163: 17.48		CLK3_HUMAN (396-565): 4.23e-12: 70.9: 25.97
+	Hs
		834049 RBY1F_HUMAN (1-280): 7.88e-46: 162: 17.48		CLK3_HUMAN (396-565): 4.23e-12: 70.9: 25.97
+	Hs
		516417 PABP1_HUMAN (10-219): 3.06e-20: 92.2: 15.09		CLK3_HUMAN (396-565): 4.23e-12: 70.9: 25.97