Interactor 1: NPM (P06748)
Nucleophosmin (NPM) (Nucleolar phosphoprotein B23) (Nucleolar protein NO38) (Numatrin)
Gene: NPM1

Interactor 2: H4 (P62805)
Histone H4
Gene: H4C1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.90 0.60 0.736

The method score is based on:

Property Details
Experiments 29104064, 30804502, 34079125, 39501047, 16107701, 20080577, 19862764
Identification Methods affinity chromatography technology, proximity labelling technology, cross-linking study, pull down, tandem affinity purification
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006334 - nucleosome assembly
GO:0016020 - membrane
and 1 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 294
Hs

1 103
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025