HitPredict

Interactor 1: HXC4 (P09017)
Homeobox protein Hox-C4 (Homeobox protein CP19) (Homeobox protein Hox-3E)
Gene: HOXC4

Interactor 2: HXB5 (P09067)
Homeobox protein Hox-B5 (Homeobox protein HHO.C10) (Homeobox protein Hox-2A) (Homeobox protein Hu-1)
Gene: HOXB5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.74 1.00 0.861

The method score is based on:

Property Details
Experiments 26186194, 28514442, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Homeodomain~Homeodomain
Common GO terms GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0005654 - nucleoplasm
and 3 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 264
Hs

1 269
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024